Neuroendocrine Control, Inflammation, and Psychological Aspects After Interdisciplinary Therapy in Obese Women

Author(s)

Moraes, Amanda dos Santos ^{[1, 2]} ; Taddeo Cipullo, Marcos Alberto ^{[1, 3]} ; Schoenardie Poli, Vanessa Fadanelli ^{[1, 2]} ; Rebelo, Renata Astride ^[1] ; Ribeiro, Eliane Beraldi ^{[1, 4]} ; Oyama, Lila Missae ^{[1, 4]} ; Andrade Silva, Stephan Garcia ^{[1, 2]} ; Damaso, Ana Raimunda ^{[1, 4]} ; Padovani, Ricardo da Costa ^{[1, 3]} ; Caranti, Danielle Arisa ^{[1, 4, 2, 5]}

Affiliation

^[1] Fed Univ Sao Paulo UNIFESP Santos, Obes Study Grp GEO, Sao Paulo, SP - Brazil

^[2] Fed Univ Sao Paulo UNIFESP Santos, Post Grad Program Interdisciplinary Hlth Sci, Sao Paulo, SP - Brazil

^[3] Fed Univ Sao Paulo UNIFESP Santos, Hlth Educ & Soc Dept, Sao Paulo, SP - Brazil

^[4] Fed Univ Sao Paulo UNIFESP Santos, Nutr, Post Grad Program Food, Sao Paulo, SP - Brazil

^[5] Fed Univ Sao Paulo UNIFESP Santos, Biosci Dept, Sao Paulo, SP - Brazil

• Document type: Journal article
• Source: Hormone and Metabolic Research; v. 51, n. 6, p. 375-380, JUN 2019.
• Web of Science Citations: 0

Abstract

Obesity is a chronic and multifactorial disease promoted by positive energy balance. The objective was to evaluate the effects of interdisciplinary therapy in the neuroendocrine control of food intake, inflammatory markers, and psychological aspects in obese women. Forty-seven obese women (43.32 +/- 5.82 years, 34.86 +/- 3.08kg/m (2) ), aged 30-50 years, participated in an interdisciplinary lifestyle change therapy, consisting of nutritional counseling, physical exercises, and psychological therapy for 36 weeks. After the long-term therapy, there was a decrease in body weight (Delta -5.36kg), BMI (Delta -2.01kg/m (2) ), abdominal (Delta -9.09cm), hip (Delta -5.03cm), and thigh (Delta -5.07cm) perimeters. There was also a significant improvement in body composition, with an increase in fat-free mass (Delta 1.60%) and reduction of body fat (Delta -3.74kg). The therapy proposed also provided an improvement in depression scores (Delta -6.63), anxiety (Delta -4.07), body image (Delta -25.25), and binge eating (Delta -5.25). There was a significant reduction in serum levels of leptin (Delta -15.62ng/ml). The interdisciplinary therapy was able to provide both, physical and psychological benefits in energy balance, which enables the use of this model as a feasible clinical strategy for the treatment of obesity. (AU)

• FAPESP's process: 11/51723-7 - Effects of interdisciplinary therapy on metabolic syndrome control in obese adults and its relationship with pro and anti inflammatory adipocytes
• Grantee: Danielle Arisa Caranti
• Support Opportunities: Regular Research Grants