Primary aromatic amines in kitchenware: Determination by liquid chromatography-tandem mass spectrometry

Autor(es)

Favaro Perez, Mary Angela ^{[1, 2]} ; Padula, Marisa ^[2] ; Moitinho, Daisy ^[2] ; Grespan Bottoli, Carla Beatriz ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, UNICAMP, Inst Chem, Campinas, SP - Brazil

^[2] Packaging Technol Ctr CETEA, Inst Food Technol ITAL, Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Chromatography A; v. 1602, p. 217-227, SEP 27 2019.
• Citações Web of Science: 2

Resumo

The aim of this paper is to develop and validate a methodology with potential for routine analysis that allows a fast and easy quantification of 19 primary aromatic amines (PAAs) in acid simulant (3% (w/v) acetic acid aqueous) in food contact materials (FCM). The main reason for studying these amines was the fact that some of them have a carcinogenic factor according to toxicological studies. To validate the method, the parameters linearity, limit of detection (LOD) and limit of quantification (LOO), precision and accuracy using an UPLC-MS/MS were evaluated. This study also analyzed 36 samples of kitchenware obtained from retail markets: 16 were made of polyamide (PA), one was made of polypropylene (PP) and 19 were made of silicone. The origins of samples were Brazil, China and Turkey. Eleven samples had levels of 4,4'-cliaminodiphenylmethane higher than permitted by legislation and five samples showed values of aniline above the limit. Considering the Mood test for polyamides, there were significant differences between the samples from Brazil and China, as well as between the colors in the silicone samples. Regarding the polyamides, the Chinese samples showed higher amounts of PAAs than the Brazilian ones, being above that allowed by legislation. Three Chinese silicone samples presented values above the legislation limit. These were all from the same importer. (C) 2019 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 18/07234-0 - 47th International Symposium on High Performance Liquid Phase Separations and Related Techniques
• Beneficiário: Carla Beatriz Grespan Bottoli
• Modalidade de apoio: Auxílio à Pesquisa - Reunião - Exterior
• Processo FAPESP: 14/50867-3 - INCT 2014: Instituto Nacional de Ciência e Tecnologia de Bioanalítica
• Beneficiário: Marco Aurelio Zezzi Arruda
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 15/26300-6 - Investigação do potencial de contaminação de alimentos por aminas aromáticas primárias (PAAs) com enfoque em utensílios domésticos coloridos
• Beneficiário: Marisa Padula
• Modalidade de apoio: Auxílio à Pesquisa - Regular