The Two-Way Polyphenols-Microbiota Interactions and Their Effects on Obesity and Related Metabolic Diseases

Autor(es)

Faraldo Correa, Telma Angelina ^{[1, 2]} ; Rogero, Marcelo Macedo ^{[2, 3]} ; Aymoto Hassimotto, Neuza Mariko ^{[1, 2]} ; Lajolo, Franco Maria ^{[1, 2]}

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sch Pharmaceut Sci, Dept Food Sci & Expt Nutr, Sao Paulo, SP - Brazil

^[2] Sao Paulo Res Fdn, CEPID FAPESP Res Innovat & Disseminat Ctr, Food Res Ctr, Sao Paulo, SP - Brazil

^[3] Univ Sao Paulo, Dept Nutr, Sch Publ Hlth, Sao Paulo, SP - Brazil

• Tipo de documento: Artigo de Revisão
• Fonte: FRONTIERS IN NUTRITION; v. 6, DEC 20 2019.
• Citações Web of Science: 0

Resumo

Metabolic diseases can change the gut microbiota composition and function, and pathogenic bacteria contribute to the development of metabolic disorders. Polyphenols may act in the gut microbiota to favor the increase of beneficial bacteria and hamper the increase of pathogenic bacteria. In addition, the microbiota may act on polyphenols to increase their bioavailability. This two-way interactions between polyphenols and the gut microbiota could affect human metabolism and reduce cardiometabolic risk. Despite the possible benefits of polyphenols for human health through modulating the microbiome, studies are scarce, and present several limitations. This review provides an overview of the polyphenol-microbiota interactions and its effects on metabolic disorders. (AU)

• Processo FAPESP: 13/07914-8 - FoRC - Centro de Pesquisa em Alimentos
• Beneficiário: Bernadette Dora Gombossy de Melo Franco
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs