Visual losses in early-onset and late-onset Parkinson's disease

Autor(es)

Feitosa-Santana, Claudia ^{[1, 2, 3]} ; Costa, Marcelo Fernandes ^{[1, 2]} ; Ferraz, Henrique Ballalai ^[4] ; Andrade, Luiz Augusto F. ^[5] ; Moura, Ana Laura ^{[6, 7]} ; Amaro Jr, Edson ; Hamer, Russell D. ^[8] ; Ventura, Dora Fix ^{[1, 2]}

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Nucleo Neurociencias & Comportamento, Sao Paulo - Brazil

^[2] Univ Sao Paulo, Inst Psicol, Dept Psicol Expt, Sao Paulo - Brazil

^[3] Neurociencia Desenvolvimento Humano, Sao Paulo - Brazil

^[4] Univ Fed Sao Paulo, Escola Paulista Med, Dept Neurol, Sao Paulo - Brazil

^[5] Hosp Israelita Albert Einstein, Sao Paulo - Brazil

^[6] ABC, Disciplina Oftalmol, Fac Med, Santo Andre, SP - Brazil

^[7] Univ Fed Sao Paulo, Dept Oftalmol, Escola Paulista Med, Sao Paulo - Brazil

^[8] Florida Atlantic Univ, Dept Psychol, Boca Raton, FL 33431 - USA

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION; v. 37, n. 5, p. A285-A293, MAY 1 2020.
• Citações Web of Science: 0

Resumo

Patients with Parkinson's disease (PD) manifest visual losses. However, it is not known whether these losses are equivalent in both early-onset (EOPD) and late-onset (LOPD) patients. We evaluated contrast sensitivity and color vision in EOPD and LOPD patients and in age-matched controls. Losses occurred in both patient groups but were more pronounced in EOPD, consistent with the notion that non-motor symptoms are affected by age of symptom onset. More studies of visual function in EOPD and LOPD patients are needed to understand how aging is related to the pathophysiology of non-motor PD symptomatology. This would permit earlier diagnosis and, perhaps, better management of the disease. (C) 2020 Optical Society of America (AU)

• Processo FAPESP: 14/26818-2 - Desenvolvimento e implantação de métodos de avaliação visual: aplicações clínicas e em modelos animais
• Beneficiário: Dora Selma Fix Ventura
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 08/58731-2 - A visão como indicador de processos lesivos na retina e no sistema nervoso central
• Beneficiário: Dora Selma Fix Ventura
• Modalidade de apoio: Auxílio à Pesquisa - Temático