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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Visual losses in early-onset and late-onset Parkinson's disease

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Author(s):
Feitosa-Santana, Claudia [1, 2, 3] ; Costa, Marcelo Fernandes [1, 2] ; Ferraz, Henrique Ballalai [4] ; Andrade, Luiz Augusto F. [5] ; Moura, Ana Laura [6, 7] ; Amaro Jr, Edson ; Hamer, Russell D. [8] ; Ventura, Dora Fix [1, 2]
Total Authors: 8
Affiliation:
[1] Univ Sao Paulo, Nucleo Neurociencias & Comportamento, Sao Paulo - Brazil
[2] Univ Sao Paulo, Inst Psicol, Dept Psicol Expt, Sao Paulo - Brazil
[3] Neurociencia Desenvolvimento Humano, Sao Paulo - Brazil
[4] Univ Fed Sao Paulo, Escola Paulista Med, Dept Neurol, Sao Paulo - Brazil
[5] Hosp Israelita Albert Einstein, Sao Paulo - Brazil
[6] ABC, Disciplina Oftalmol, Fac Med, Santo Andre, SP - Brazil
[7] Univ Fed Sao Paulo, Dept Oftalmol, Escola Paulista Med, Sao Paulo - Brazil
[8] Florida Atlantic Univ, Dept Psychol, Boca Raton, FL 33431 - USA
Total Affiliations: 8
Document type: Journal article
Source: JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION; v. 37, n. 5, p. A285-A293, MAY 1 2020.
Web of Science Citations: 0
Abstract

Patients with Parkinson's disease (PD) manifest visual losses. However, it is not known whether these losses are equivalent in both early-onset (EOPD) and late-onset (LOPD) patients. We evaluated contrast sensitivity and color vision in EOPD and LOPD patients and in age-matched controls. Losses occurred in both patient groups but were more pronounced in EOPD, consistent with the notion that non-motor symptoms are affected by age of symptom onset. More studies of visual function in EOPD and LOPD patients are needed to understand how aging is related to the pathophysiology of non-motor PD symptomatology. This would permit earlier diagnosis and, perhaps, better management of the disease. (C) 2020 Optical Society of America (AU)

FAPESP's process: 14/26818-2 - Development and implementation of visual evaluation methods: clinical applications and animal models
Grantee:Dora Selma Fix Ventura
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 08/58731-2 - Vision as a sensitive indicator of conditions threatening retinal and central nervous system function
Grantee:Dora Selma Fix Ventura
Support Opportunities: Research Projects - Thematic Grants