Evolutionary History of the Globin Gene Family in Annelids

Autor(es)

Belato, Flavia A. ^[1] ; Coates, Christopher J. ^[2] ; Halanych, Kenneth M. ^[3] ; Weber, Roy E. ^[4] ; Costa-Paiva, Elisa M. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Inst Biosci, Dept Zool, Sao Paulo - Brazil

^[2] Swansea Univ, Coll Sci, Dept Biosci, Swansea, W Glam - Wales

^[3] Auburn Univ, Dept Biol Sci, Molette Biol Lab Environm & Climate Change Studie, Auburn, AL 36849 - USA

^[4] Aarhus Univ, Dept Biol, Zoophysiol, Aarhus - Denmark

• Tipo de documento: Artigo Científico
• Fonte: GENOME BIOLOGY AND EVOLUTION; v. 12, n. 10, p. 1719-1733, OCT 2020.
• Citações Web of Science: 1

Resumo

Animals depend on the sequential oxidation of organic molecules to survive; thus, oxygen-carrying/transporting proteins play a fundamental role in aerobic metabolism. Globins are the most common and widespread group of respiratory proteins. They can be divided into three types: circulating intracellular, noncirculating intracellular, and extracellular, all of which have been reported in annelids. The diversity of oxygen transport proteins has been underestimated across metazoans. We probed 250 annelid transcriptomes in search of globin diversity in order to elucidate the evolutionary history of this gene family within this phylum. We report two new globin types in annelids, namely androglobins and cytoglobins. Although cytoglobins and myoglobins from vertebrates and from invertebrates are referred to by the same name, our data show they are not genuine orthologs. Our phylogenetic analyses show that extracellular globins from annelids are more closely related to extracellular globins from other metazoans than to the intracellular globins of annelids. Broadly, our findings indicate that multiple gene duplication and neo-functionalization events shaped the evolutionary history of the globin family. (AU)

• Processo FAPESP: 16/06114-6 - O Sistema Terra e a evolução da vida durante o Neoproterozoico
• Beneficiário: Ricardo Ivan Ferreira da Trindade
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 18/20268-1 - Fisiologia de Análogos Modernos da fauna Ediacarana e Cambriana
• Beneficiário: Elisa Maria Costa e Silva de Paiva
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado