Understanding the mixed alkali effect on the sinterability and in vitro performance of bioactive glasses

Autor(es)

Crovace, Murilo C. ^[1] ; Soares, Viviane O. ^[2] ; Rodrigues, Ana Candida M. ^[1] ; Peitl, Oscar ^[1] ; Raucci, Larissa M. S. C. ^[3] ; de Oliveira, Paulo T. ^[3] ; Zanotto, Edgar D. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Fed Sao Carlos, Dept Mat Engn, Vitreous Mat Lab LaMaV, Sao Carlos, SP - Brazil

^[2] Univ Estadual Maringa, Dept Sci, Goioere, PR - Brazil

^[3] Univ Sao Paulo, Sch Dent Ribeirao Preto, Cell Culture Lab, Ribeirao Preto, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of the European Ceramic Society; v. 41, n. 7, p. 4391-4405, JUL 2021.
• Citações Web of Science: 2

Resumo

Bioglass 45S5 is widely known for its ability to regenerate bone. However, this glass cannot be fully densified by viscous flow due to its very high tendency for crystallization. In this work, we evaluate the sintering and bioactivity of Bioglass 45S5-based compositions in which Na2O is incrementally replaced by K2O. Our sintering tests demonstrated that the densification of Bioglass 45S5 powders can be significantly enhanced due to a decreased crystallization tendency. The composition in which half of the original Na2O content was substituted by K2O exhibits the highest densification rate, evidencing the mixed alkali effect (MAE) in the viscous-flowdriven sintering process. The replacement of Na2O by K2O significantly improved both the densification rate and the in vitro performance. These results are very relevant for this particular glass and also for the design of new bioactive glasses with improved sinterability. (AU)

• Processo FAPESP: 08/11539-0 - Obtenção de scaffolds através da sinterização do Biosilicato® vítreo com cristalização concorrente
• Beneficiário: Murilo Camuri Crovace
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 13/07793-6 - CEPIV - Centro de Ensino, Pesquisa e Inovação em Vidros
• Beneficiário: Edgar Dutra Zanotto
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs
• Processo FAPESP: 13/07059-0 - Scaffolds vitrocerâmicos bioativos aplicáveis à ortopedia e odontologia obtidos através de tecnologias tridimensionais
• Beneficiário: Murilo Camuri Crovace
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado