Production of oral films based on pre-gelatinized starch, CMC and HPMC for delivery of bioactive compounds extract from acerola industrial waste

Autor(es)

Tedesco, Marcela Perozzi ^[1] ; dos Santos Garcia, Vitor Augusto ^[1] ; Borges, Josiane Goncalves ^[1] ; Osiro, Denise ^[2] ; Vanin, Fernanda Maria ^[1] ; Pedroso Yoshida, Cristiana Maria ^[3] ; de Carvalho, Rosemary Aparecida ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Fac Anim Sci & Food Engn, Av Duque Caxias Norte 225, BR-13635900 Pirassununga, SP - Brazil

^[2] Univ Ctr Guaxupe Educ Fdn, Av Dona Floriana 463, BR-37800000 Guaxupe, MG - Brazil

^[3] Univ Fed Sao Paulo, Inst Environm Chem & Pharmaceut Sci, Rua Sao Nicolau 210, BR-09913030 Diadema, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: INDUSTRIAL CROPS AND PRODUCTS; v. 170, OCT 15 2021.
• Citações Web of Science: 0

Resumo

The residue from the processing of acerola, due to the concentration of active compounds, and antioxidant potential has aroused interest in its application. In this context, this study aimed to produce and characterization oral films based on carboxymethyl cellulose (CMC), hydroxypropyl methylcellulose (HPMC) and pre-gelatinized starch with the incorporation of ethanolic extract of dehydrated acerola industrial waste (EEDAIW) using tape -casting technique. The rheological properties of filmogenic solutions of CMC, HPMC, and starch were assessed. Oral films were characterized in relation to color parameters, mechanical properties, surface pH, contact angle, Fourier transform infrared (FTIR) spectroscopy, atomic force microscopy, and stability in relation to total phenolic compounds. It was found that apparent viscosity decreased with the deformation rate and the expected behavior of pseudoplastic fluids, regardless of the polymer used. In general, the addition of EEDAIW in the films led to a reduction in the tensile strength of the films and an increase in the contact angle values; however, the surface pH of the films remained close to the oral pH (6.8). From the FTIR, it was found that even after the addition of EEDAIW, all films showed predominant absorption bands, characteristic of the polymer used. It was found that after 84 days, CMC-based films had a higher concentration of total phenolic compounds when compared to HPMC and starch oral films. (AU)

• Processo FAPESP: 16/16250-4 - Extração e veiculação de compostos ativos do resíduo industrial de acerola e camu-camu em filmes à base de polímeros naturais produzidos por tape casting
• Beneficiário: Rosemary Aparecida de Carvalho
• Modalidade de apoio: Auxílio à Pesquisa - Regular