| Texto completo | |
| Autor(es): |
Abdeshahian, Peyman
[1]
;
Ascencio, Jesus Jimenez
[1]
;
Philippini, Rafael R.
[1]
;
Antunes, Felipe Antonio Fernandes
[1]
;
Ingle, Avinash P.
[2]
;
Abdeshahian, Mojgan
[3]
;
dos Santos, Julio Cesar
[1]
;
da Silva, Silvio Silverio
[1]
Número total de Autores: 8
|
| Afiliação do(s) autor(es): | [1] Univ Sao Paulo, Engn Sch Lorena, Dept Biotechnol, BR-12602810 Sao Paulo - Brazil
[2] Panjabrao Deshmukh Krishi Vidyapeeth, Dept Agr Bot, Biotechnol Ctr, Akola 444104 - India
[3] Payame Noor Univ PNU, Dept Agr Sci, Tehran 193954697 - Iran
Número total de Afiliações: 3
|
| Tipo de documento: | Artigo Científico |
| Fonte: | SUSTAINABILITY; v. 13, n. 17 SEP 2021. |
| Citações Web of Science: | 0 |
| Resumo | |
Lasiodiplodan is a beta-glucan polymer with different interesting characteristics, including therapeutic properties. It is an extracellular product, which is produced by the filamentous fungus Lasiodiplodia theobromae, using glucose as a substrate. In the present work, the production of lasiodiplodan was studied by the utilization of sugarcane straw as a low-cost carbon source. Glucose-rich sugarcane straw hydrolysate was obtained by a sequential pretreatment with dilute nitric acid (1% v/v) and sodium hydroxide (1% w/v), followed by enzymatic hydrolysis. The fermentation process was conducted by the cultivation of the strain Lasiodiplodia theobromae CCT3966 in sugarcane straw hydrolysate in a shake flask at 28 degrees C for 114 h. It was found that hydrolysate obtained after enzymatic hydrolysis contained 47.10 gL(-1) of glucose. Fermentation experiments of lasiodiplodan synthesis showed that the peak yield and productivity of 0.054 gg(-1) glucose consumed and 0.016 gL(-1) h(-1), respectively, were obtained at 72 h fermentation time. Fungal growth, glucose consumption, and lasiodiplodan production from sugarcane straw hydrolysate presented a similar pattern to kinetic models. The study on the chemical structure of lasiodiplodan produced showed it had a beta-glucan construction. The current study revealed that sugarcane straw is a promising substrate for the production of lasiodiplodan. (AU) | |
| Processo FAPESP: | 18/14095-7 - Novas estratégias integradas para produção econômica de beta-glucana a partir de resíduos agroindustriais e roteiro para comercialização no Brasil |
| Beneficiário: | Peyman Abdeshahian |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |
| Processo FAPESP: | 16/10636-8 - Da fábrica celular à biorrefinaria integrada Biodiesel-Bioetanol: uma abordagem sistêmica aplicada a problemas complexos em micro e macroescalas |
| Beneficiário: | Roberto de Campos Giordano |
| Modalidade de apoio: | Auxílio à Pesquisa - Programa BIOEN - Temático |