| Texto completo | |
| Autor(es): |
Goya, Thiago Tanaka
[1]
;
Ferreira-Silva, Rosyvaldo
[2]
;
Gara, Elisangela Macedo
[2]
;
Guerra, Renan Segalla
[1]
;
Ferreira Barbosa, Eline Rozaria
[1]
;
Toschi-Dias, Edgar
[1]
;
Cunha, Paulo Jannuzzi
[3, 4]
;
Negrao, Carlos Eduardo
[1, 5]
;
Lorenzi-Filho, Geraldo
[1]
;
Ueno-Pardi, Linda Massako
[2, 3, 1]
Número total de Autores: 10
|
| Afiliação do(s) autor(es): | [1] Univ Sao Paulo, Hosp Clin HCFMUSP, Fac Med, Intituto Coracao InCor, Sao Paulo, SP - Brazil
[2] Univ Sao Paulo, Escola Artes Ciencias & Humanidades, Sao Paulo, SP - Brazil
[3] Univ Sao Paulo, Nucleo Apoio Pesquisa Neurociencia Aplicada NAPNA, Sao Paulo, SP - Brazil
[4] Univ Sao Paulo, Hosp Clin HCFMUSP, Fac Med, Dept Psiquiatria, Sao Paulo, SP - Brazil
[5] Univ Sao Paulo, Escola Educ Fis & Esportes, Sao Paulo, SP - Brazil
Número total de Afiliações: 5
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Clinics; v. 76, 2021. |
| Citações Web of Science: | 0 |
| Resumo | |
OBJECTIVE: To investigate the effects of exercise training (ET) on muscle sympathetic nerve activity (MSNA) and executive performance during Stroop Color Word Test (SCWT) also referred to as mental stress test. METHODS: Forty-four individuals with obstructive sleep apnea (OSA) and no significant co-morbidities were randomized into 2 groups; 15 individuals completed the control period, and 18 individuals completed the ET. Mini-mental state of examination and intelligence quotient were also assessed. MSNA assessed by microneurography, heart rate by electrocardiography, blood pressure (automated oscillometric device) were measured at baseline and during 3 min of the SCWT. Peak oxygen uptake (VO2 peak) was evaluated using cardiopulmonary exercise testing. Executive performance was assessed by the total correct responses during 3 min of the SCWT. ET consisted of 3 weekly sessions of aerobic exercise, resistance exercises, and flexibility (72 sessions, achieved in 40±3.9 weeks). RESULTS: Baseline parameters were similar between groups. Heart rate, blood pressure, and MSNA responses during SCWT were similar between groups (p>0.05). The comparisons between groups showed that the changes in VO2 (4.7±0.8 vs -1.2±0.4) and apnea-hypopnea index (-7.4±3.1 vs 5.5±3.3) in the exercise-trained group were significantly greater than those observed in the control group respectively (p<0.05) after intervention. ET reduced MSNA responses (p<0.05) and significantly increased the number of correct answers (12.4%) during SCWT. The number of correct answers was unchanged in the control group (p>0.05). CONCLUSIONS: ET improves sympathetic response and executive performance during SCWT, suggesting a prominent positive impact of ET on prefrontal functioning in individuals with OSA. ClinicalTrials.gov: NCT002289625. (AU) | |
| Processo FAPESP: | 10/15064-6 - Efeitos do treinamento físico na estrutura e metabolismo cerebral, cognição e controle neurovascular em indivíduos com apnéia obstrutiva do sono |
| Beneficiário: | Linda Massako Ueno Pardi |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |