Mini-review: The suspected non-Alzheimer's disease pathophysiology

Autor(es)

Rizzi, Liara ^[1] ; Balthazar, Marcio L. F. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, Dept Neurol, UNICAMP, Campinas, SP - Brazil

• Tipo de documento: Artigo de Revisão
• Fonte: Neuroscience Letters; v. 764, NOV 1 2021.
• Citações Web of Science: 0

Resumo

Suspected non-Alzheimer's disease pathophysiology (SNAP) is a biomarker-based concept that underlying etiology has not been completely understood. Refers to a group of individuals that are negative for amyloid biomarkers and positive for p-Tau and/or neurodegeneration. SNAP causes great research interest because it is not clear if they have a different biological basis from Alzheimer's disease (AD), or are in an early stage of AD itself. The pathological processes behind SNAP need to be clarified. This mini-review aims to summarize the main characteristics of SNAP, besides reporting challenges and promising biomarkers related to the concept. (AU)

• Processo FAPESP: 18/15571-7 - Mapeando a progressão do declínio cognitivo subjetivo para comprometimento cognitivo leve e demência da Doença de Alzheimer com biomarcadores multimodais
• Beneficiário: Marcio Luiz Figueredo Balthazar
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores - Fase 2
• Processo FAPESP: 19/23028-4 - Caracterização de indivíduos com suspeita de fisiopatologia não-Alzheimer (SNAP) por meio de biomarcadores multimodais
• Beneficiário: Liara Rizzi
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado