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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Protein-Based 3D Biofabrication of Biomaterials

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Autor(es):
Mirzaei, Mahta [1] ; Okoro, Oseweuba Valentine [1] ; Nie, Lei [2] ; Petri, Denise Freitas Siqueira [3] ; Shavandi, Amin [1]
Número total de Autores: 5
Afiliação do(s) autor(es):
[1] Univ Libre Bruxelles ULB, BioMatter Unit, Ecole Polytech Bruxelles, B-1050 Brussels - Belgium
[2] Xinyang Normal Univ, Coll Life Sci, Xinyang 464000 - Peoples R China
[3] Univ Sao Paulo, Inst Chem, Fundamental Chem Dept, BR-05508000 Sao Paulo - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo de Revisão
Fonte: BIOENGINEERING-BASEL; v. 8, n. 4 APR 2021.
Citações Web of Science: 6
Resumo

Protein/peptide-based hydrogel biomaterial inks with the ability to incorporate various cells and mimic the extracellular matrix's function are promising candidates for 3D printing and biomaterials engineering. This is because proteins contain multiple functional groups as reactive sites for enzymatic, chemical modification or physical gelation or cross-linking, which is essential for the filament formation and printing processes in general. The primary mechanism in the protein gelation process is the unfolding of its native structure and its aggregation into a gel network. This network is then stabilized through both noncovalent and covalent cross-link. Diverse proteins and polypeptides can be obtained from humans, animals, or plants or can be synthetically engineered. In this review, we describe the major proteins that have been used for 3D printing, highlight their physicochemical properties in relation to 3D printing and their various tissue engineering application are discussed. (AU)

Processo FAPESP: 19/22671-0 - Conjugados de peptídeos e polissacarídeos como materiais antimicrobianos para impressão 3D
Beneficiário:Denise Freitas Siqueira Petri
Modalidade de apoio: Auxílio à Pesquisa - Regular