| Full text | |
| Author(s): |
Mirzaei, Mahta
[1]
;
Okoro, Oseweuba Valentine
[1]
;
Nie, Lei
[2]
;
Petri, Denise Freitas Siqueira
[3]
;
Shavandi, Amin
[1]
Total Authors: 5
|
| Affiliation: | [1] Univ Libre Bruxelles ULB, BioMatter Unit, Ecole Polytech Bruxelles, B-1050 Brussels - Belgium
[2] Xinyang Normal Univ, Coll Life Sci, Xinyang 464000 - Peoples R China
[3] Univ Sao Paulo, Inst Chem, Fundamental Chem Dept, BR-05508000 Sao Paulo - Brazil
Total Affiliations: 3
|
| Document type: | Review article |
| Source: | BIOENGINEERING-BASEL; v. 8, n. 4 APR 2021. |
| Web of Science Citations: | 6 |
| Abstract | |
Protein/peptide-based hydrogel biomaterial inks with the ability to incorporate various cells and mimic the extracellular matrix's function are promising candidates for 3D printing and biomaterials engineering. This is because proteins contain multiple functional groups as reactive sites for enzymatic, chemical modification or physical gelation or cross-linking, which is essential for the filament formation and printing processes in general. The primary mechanism in the protein gelation process is the unfolding of its native structure and its aggregation into a gel network. This network is then stabilized through both noncovalent and covalent cross-link. Diverse proteins and polypeptides can be obtained from humans, animals, or plants or can be synthetically engineered. In this review, we describe the major proteins that have been used for 3D printing, highlight their physicochemical properties in relation to 3D printing and their various tissue engineering application are discussed. (AU) | |
| FAPESP's process: | 19/22671-0 - Peptides-polysaccharides conjugates as antimicrobial materials for 3D printing |
| Grantee: | Denise Freitas Siqueira Petri |
| Support Opportunities: | Regular Research Grants |