| Texto completo | |
| Autor(es): |
Smith, Bradley J.
;
Martins-de-Souza, Daniel
;
Simionato, AVC
Número total de Autores: 3
|
| Tipo de documento: | Artigo Científico |
| Fonte: | SEPARATION TECHNIQUES APPLIED TO OMICS SCIENCES: FROM PRINCIPLES TO RELEVANT APPLICATIONS; v. 1336, p. 13-pg., 2021-01-01. |
| Resumo | |
Since its inception, liquid chromatography-mass spectrometry (LC-MS) has been continuously improved upon in many aspects, including instrument capabilities, sensitivity, and resolution. Moreover, the costs to purchase and operate mass spectrometers and -liquid chromatography systems have decreased, thus increasing affordability and availability in sectors outside of academic and industrial research. Processing power has also grown immensely, cutting the time required to analyze samples, allowing more data to be feasibly processed, and allowing for standardized processing pipelines. As a result, proteomics via LC-MS has become popular in many areas of biological sciences, forging an important seat for itself in targeted and untargeted assays, pure and applied science, the laboratory, and the clinic. In this chapter, many of these applications of LC-MS-based proteomics and an outline of how they can be executed will be covered. Since the field of personalized medicine has matured alongside proteomics, it has also come to rely on various mass spectrometry methods and will be elaborated upon as well. As time goes on and mass spectrometry evolves, there is no doubt that its presence in these areas, and others, will only continue to grow. (AU) | |
| Processo FAPESP: | 14/10068-4 - EMU concedido no processo 13/08711-3: espectrômetro de massas Waters SYNAPT G2-Si HDMs + nanoACQUITY UPLC |
| Beneficiário: | Daniel Martins-de-Souza |
| Modalidade de apoio: | Auxílio à Pesquisa - Programa Equipamentos Multiusuários |
| Processo FAPESP: | 16/07948-8 - Papel da fosfodiesterase CNP associada a mielina com a esquizofrenia |
| Beneficiário: | Bradley Joseph Smith |
| Modalidade de apoio: | Bolsas no Brasil - Mestrado |
| Processo FAPESP: | 19/05747-3 - A manutenção e a maturação de uma linhagem celular de oligodendrócitos |
| Beneficiário: | Bradley Joseph Smith |
| Modalidade de apoio: | Bolsas no Brasil - Programa Capacitação - Treinamento Técnico |
| Processo FAPESP: | 19/00098-7 - EMU concedido no processo 2017/25588-1: cromatógrafo Acquity UPLC I-Class |
| Beneficiário: | Daniel Martins-de-Souza |
| Modalidade de apoio: | Auxílio à Pesquisa - Programa Equipamentos Multiusuários |
| Processo FAPESP: | 17/25588-1 - Da compreensão básica a biomarcadores clínicos para a esquizofrenia: um estudo multidisciplinar centrado na neuroproteômica |
| Beneficiário: | Daniel Martins-de-Souza |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |