Supplementation of carotenoids from peach palm waste (Bactris gasipaes) obtained with an ionic liquid mediated process displays kidney anti-inflammatory and antioxidant outcomes

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Santamarina, Aline B. ; Mesquita, Leonardo M. de Souza ; Casagrande, Breno P. ; Sertorio, Marcela N. ; de Souza, Daniel Vitor ; V. Mennitti, Lais ; Ribeiro, Daniel A. ; Estadella, Debora ; Ventura, Sonia P. M. ; de Rosso, Veridiana V. ; Pisani, Luciana P.

• Tipo de documento: Artigo Científico
• Fonte: FOOD CHEMISTRY-X; v. 13, p. 10-pg., 2022-03-30.

Resumo

Sustainable extraction processes based on alternative solvents to recover bioactive compounds of different raw materials have been highlighted as excellent alternatives to supply the needs of society towards a bioeconomy strategy. Little is known about the safety and biological effect of compounds extracted by these processes. In this work, camtenoids from Bactris gasipaes wastes obtained by an IL-based process were investigated in terms of safety, anti-inflammatory and, antioxidant activity in a high-fat-diet animal model on the kidney. Wistar rats were supplemented or not by camtenoids extracted with IL or VOS. The animals supplemented with carotenoids had lower weight than control and high-fat diets. In the animals supplemented with carotenoids, the group IL improved anti-inflammatory and antioxidant activity compared with carotenoids obtained by VOS. Also, the group HFD-VOS showed moderate-severe injuries on the kidney. Then, ILs could represent a novel tool for natural pigments safely applied to food industry. (AU)

• Processo FAPESP: 16/23242-8 - Extração de carotenóides de Bactris gasipaes com líquidos iônicos e sua aplicação em modelo de programação metabólica
• Beneficiário: Leonardo Mendes de Souza Mesquita
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 18/10705-5 - Extração de carotenoides de Bactris gasipaes mediada por soluções aquosas de líquidos iônicos tensoativos e surfactantes: uma abordagem de química verde e sustentável
• Beneficiário: Leonardo Mendes de Souza Mesquita
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Doutorado
• Processo FAPESP: 20/04448-0 - O efeito de diferentes tipos de ácidos graxos associado à dieta hipoglicídica na modulação inflamatória, epigenética e mitocôndrial no tratamento da Obesidade
• Beneficiário: Aline Boveto Santamarina
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado