Targeted and non-targeted analysis of pesticides and aflatoxins in baby foods by liquid chromatography coupled to quadrupole Orbitrap mass spectrometry

Autor(es)

Prata, Rafaela ; Lopez-Ruiz, Rosalia ; Petrarca, Mateus Henrique ; Godoy, Helena Teixeira ; Frenich, Antonia Garrido ; Romero-Gonzalez, Roberto

• Tipo de documento: Artigo Científico
• Fonte: FOOD CONTROL; v. 139, p. 10-pg., 2022-05-08.

Resumo

In this study, 21 pesticides and 4 aflatoxins were monitored in baby food marketed in Brazil, applying ultra -high-performance liquid chromatography coupled to quadrupole-Orbitrap mass spectrometry (UHPLC-Q-OrbitrapMS). The quick, easy, cheap, effective, rugged, and safe (QuEChERS) extraction method combined with dispersive solid-phase extraction (d-SPE) clean-up was applied and primary secondary amine (PSA), octadecylsilane (C18) and C18 with silica coated with zirconium dioxide (Z-Sep+) were used during the clean-up stage. Suitable performance criteria, set by the SANTE/2020/12830 guidelines, were achieved, and therefore, all targeted analytes were successfully validated. The method was applied to the analysis of 50 baby food samples. Cypermethrin was detected at 10.3 mu g kg(-1) (above maximum residue level (MRL) established by the European Union (EU)). Furthermore, suspect screening analysis was performed for reliable identification of contaminants not included in this study such as other pesticides, mycotoxins, hormones, veterinary drugs and their metabolites. Finally 10 pesticides and one metabolite were detected, demonstrating the suitability of the proposed approach. (AU)

• Processo FAPESP: 17/11635-8 - Resíduos e contaminantes em alimentos infantis e mamadeiras: desenvolvimento e validação de métodos analíticos
• Beneficiário: Helena Teixeira Godoy
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 19/04727-9 - Desenvolvimento e validação de métodos analíticos para a determinação de contaminantes de processamento e resíduos de agroquímicos em alimentos infantis
• Beneficiário: Rafaela Prata
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto
• Processo FAPESP: 20/01974-2 - Determinação de resíduos e contaminantes em alimentos infantis comercializados no Brasil por UHPLC-QqQ-MS/MS: desenvolvimento e validação de métodos
• Beneficiário: Rafaela Prata
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Doutorado Direto