alpha-Arylation and Alkynylation of Cyclic alpha-Iodoenones Using Palladium-Catalyzed Cross-Coupling Reactions with Trifluoroborate Salts

Autor(es)

Gueogjian, Kemilla ; Singh, Fateh V. ; Pena, Jesus M. ; Amaral, Monica F. Z. J. ; Stefani, Helio A.

• Tipo de documento: Artigo Científico
• Fonte: Synlett; v. N/A, n. 3, p. 6-pg., 2010-02-01.

Resumo

An expeditious synthesis of alpha-aryl- and alpha-alkynylcyclo-hexenones is described and illustrated by palladium-catalyzed cross-coupling reaction of cyclic alpha-iodoenones with potassium aryltrifluoroborate salts. This procedure offers easy access to alpha-arylated and alkynylated cyclohexenones functionalized with electrondonor and -acceptor substituents in good yields. (AU)

• Processo FAPESP: 07/59404-2 - Reações entre sais de potássio de organotrifluoroboratos e espécies eletrofílicas de telúrio e haletos orgânicos
• Beneficiário: Helio Alexandre Stefani
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 07/51466-9 - Sintese e aplicacao de sais de potassio de 1-bromo-1-trifluoroborato-! e 1-fenil-1-trifluoroborato eteno e 1-bromo-1-n-butitelurio-! 1-fenil-1-n-butitelurio eteno.
• Beneficiário: Fateh Veer Singh
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado