| Texto completo | |
| Autor(es): |
Jorge, Luciana
;
da Pureza, Demilto Y.
;
Dias, Danielle da Silva
;
Conti, Filipe Fernandes
;
Irigoyen, Maria-Claudia
;
De Angelis, Katia
Número total de Autores: 6
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Experimental Diabetes Research; v. N/A, p. 5-pg., 2012-01-01. |
| Resumo | |
The objective of the present study was to investigate the effects of an acute aerobic exercise on arterial pressure (AP), heart rate (HR), and baroreflex sensitivity (BRS) in STZ-induced diabetic rats. Male Wistar rats were divided into control (n = 8) and diabetic (n = 8) groups. AP, HR, and BRS, which were measured by tachycardic and bradycardic (BR) responses to AP changes, were evaluated at rest (R) and postexercise session (PE) on a treadmill. At rest, STZ diabetes induced AP and HR reductions, associated with BR impairment. Attenuation in resting diabetes-induced AP (R: 103 +/- 2 versus PE: 111 +/- 3 mmHg) and HR (R: 290 +/- 7 versus PE:328 +/- 10 bpm) reductions and BR dysfunction (R: -0.70 +/- 0.06 versus PE:-1.21 +/- 0.09 bpm/mmHg) was observed in the postexercise period. In conclusion, the hemodynamic and arterial baro-mediated control of circulation improvement in the postexercise period reinforces the role of exercise in the management of cardiovascular risk in diabetes. (AU) | |
| Processo FAPESP: | 07/57595-5 - Efeitos do treinamento físico no controle autônomo cardiovascular em fêmeas saudáveis e submetidas à privação dos hormônios ovarianos: papel do estresse oxidativo |
| Beneficiário: | Kátia de Angelis Lobo D Avila |
| Modalidade de apoio: | Auxílio à Pesquisa - Jovens Pesquisadores |
| Processo FAPESP: | 07/58942-0 - Da bancada à clínica: desenvolvimento de biomarcadores como preditores da resposta à terapêutica e lesão de órgãos-alvo na hipertensão arterial sistemática |
| Beneficiário: | Eduardo Moacyr Krieger |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |