Ecotoxicological risk assessment of the "Acid Black 210" dye

Autor(es)

Rocha, Otavio Pelegrino ; Cesila, Cibele Aparecida ; Christovam, Elisa Maria ; de Moraes Barros, Silvia Berlanga ; Boldrin Zanoni, Maria Valnice ; de Oliveira, Danielle Palma

• Tipo de documento: Artigo Científico
• Fonte: Toxicology; v. 376, p. 7-pg., 2017-02-01.

Resumo

The "Acid Black 210" dye is one of the most used black dyes by the leather industry. This compound contains three azo groups in its chemical structure, and has been quoted as a non-regulated dye with toxicological concern, since it could generate carcinogenic aromatic amines. The objective of this study was to perform the ecotoxicological risk assessment of this dye through testing its toxicity in vitro and in vivo with the Ames test, the Comet assay, the Daphnia similis test, and the zebrafish embryo acute toxicity test. Moreover, we evaluated the presence of this dye in environmental samples related with a tannery industry. All the tests performed were negative, with the exception of the Ames test with the Salmonella typhimurium TA98 strain, which resulted in a low mutagenic potency. Due to the low concentrations of the "Acid Black 210" dye found in tannery effluents, and the high concentrations where any toxic activity is occasionally described, we concluded that this dye is safe from the ecotoxicological point of view in the areas evaluated and in the light of the current knowledge. (C) 2016 Elsevier Ireland Ltd. All rights reserved. (AU)

• Processo FAPESP: 08/10449-7 - Avaliação da ocorrência, toxicidade/genotoxicidade e processos para degradação de corantes em efluentes e águas superficiais
• Beneficiário: Maria Valnice Boldrin
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 13/09317-7 - Avaliação do risco ecogenotoxicológico da utilização de corantes têxteis.
• Beneficiário: Otávio Pelegrino Rocha
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 13/06172-8 - Avaliação do potencial mutagênico de corantes têxteis por meio do ensaio de micronúcleo
• Beneficiário: Cibele Aparecida Cesila
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 13/24340-5 - Desenvolvimento e validação de método em LC-ESI-MS/MS para determinação do corante acid black 210 em efluentes de curtume e avaliação da genotoxicidade
• Beneficiário: Elisa Maria Christovam
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica