Neutrophil Migration and Adhesion Molecule Expression after Acute High-Intensity Street Dance Exercise

Autor(es)

Borges, Leandro ; Dermargos, Alexandre ; Gray, Stuart ; Barros Silva, Maysa B. ; Santos, Vinicius ; Pithon-Curi, Tania Cristina ; Gorjao, Renata ; Hatanaka, Elaine

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF IMMUNOLOGY RESEARCH; v. 2018, p. 6-pg., 2018-01-01.

Resumo

The physical demands of street dancing may result in inflammation and changes in leukocyte numbers/function, impairing the health of dancers. Herein, we investigated the effect of street dancing on inflammation, adhesion molecules, and neutrophil function. Fifteen amateur dancers (mean +/- SE: age 22.4 +/- 1.08 years, BMI 24.8 +/- 0.69 kg/m(2), and body fat 12.3 +/- 1.52%) participated in a single high-intensity street dance class. Blood samples were taken before and after the class. The dance class had no effect on the plasma concentration of CRP, TNF-alpha, IL-6, IL-10, and IL-8; however, we noted an increase in levels of IL-1 beta (4.06%) and sL-selectin (17.67%). The dance class resulted in a 12.36% increase in neutrophil counts, while neutrophil CD62L expression and migration were reduced (25.27% and 78.92%, resp.). After the dance class, neutrophil production of IL-8 and TNF-alpha increased, respectively, by 59.75% and 49.23%, in the control condition, and 43.55% and 32.22%, after LPS stimulation. A single bout of street dancing induced inflammation and reduced neutrophil migration and adhesion molecule expression. These findings may contribute to a better understanding of the susceptibility to infection after acute dance exercise. (AU)

• Processo FAPESP: 14/21185-1 - Efeito do treinamento físico moderado sobre o estado inflamatório e as funções leucocitárias de indivíduos diabéticos
• Beneficiário: Elaine Hatanaka Dermargos
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 11/21441-0 - Instalação e resolução do processo inflamatório em bailarinas clássicas: estudo das alterações sistêmicas e leucocitárias
• Beneficiário: Elaine Hatanaka Dermargos
• Modalidade de apoio: Auxílio à Pesquisa - Regular