On the release of fluoride from biofilm reservoirs during a cariogenic challenge: anin situstudy

Autor(es)

Souza, Joao G. S. ; Del Bel Cury, Altair A. ; Cury, Jaime A. ; Tenuta, Livia M. A.

• Tipo de documento: Artigo Científico
• Fonte: BIOFOULING; v. 36, n. 7, p. 7-pg., 2020-09-29.

Resumo

Biofilm fluoride reservoirs may be a source of fluoride to the fluid phase during a sugar challenge reducing tooth mineral loss. However, the evidence for that is conflicting and has not been studied in biofilms containing different fluoride levels. In order to test fluoride release from biofilms with distinct fluoride concentrations, biofilms were grownin situexposed to a combination of placebo, calcium and fluoride rinses forming biofilms with no (fluoride-free rinses), low (fluoride-only rinses) or high (calcium followed by fluoride rinses) fluoride concentrations, and collected before and 5 min after a sucrose challenge. Rinsing with fluoride increased fluoride concentration in the biofilm (p < 0.05), mainly when a calcium pre-rinse was used before the fluoride (p < 0.05). However, after a sugar challenge, no significant increase in the biofilm fluid fluoride concentration was observed, even in the fluoride-rich biofilms (p > 0.05). Fluoride-rich biofilms do not release fluoride to the fluid phase during a sugar challenge. (AU)

• Processo FAPESP: 14/00799-1 - Efeito de um pré-bochecho com cálcio na eficácia anticárie de solução fluoretada: estudo in situ
• Beneficiário: João Gabriel Silva Souza
• Modalidade de apoio: Bolsas no Brasil - Mestrado