Sodium bicarbonate and beta-alanine supplementation: Is combining both better than either alone? A systematic review and meta-analysis

Autor(es)

Curran-Bowen, Terence ; da Silva, Andre Guedes ; Barreto, Gabriel ; Buckley, John ; Saunders, Bryan

• Tipo de documento: Artigo Científico
• Fonte: BIOLOGY OF SPORT; v. 41, n. 3, p. 9-pg., 2024-01-01.

Resumo

This systematic review and meta-analysis aimed to determine the effect of combined beta-alanine (BA) and sodium bicarbonate (SB) supplementation on exercise capacity and performance. Four databases (PubMed, SPORTDiscus, Web Of Science and MEDLINE) were searched using relevant terms for studies involving healthy (e.g. no chronic diseases or conditions) male or female adults of any training status (athletes, physically active and nonathletes) and that investigated BA and SB in isolation and combination at any dose on an exercise outcome. Ten studies, totalling 243 individuals, met the criteria with 12 outcomes for each nutritional supplement. No ergogenic effect was detected in this meta-analysis for BA (SMD = 0.18, 95% CI: -0.06; 0.43, p = 0.13, tau2 = 0, tau = 0, I2 = 0.0%) or SB (SMD = 0.17, 95% CI: -0.08; 0.41, p = 0.16, tau2 = 0, tau = 0, I2 = 0.0%) in isolation. However, there was a beneficial effect for the combination of BA and SB (SMD = 0.32, 95% CI: 0.07; 0.57, p = 0.02, tau2 = 0, tau = 0, I2 = 0.0%). Meta-regression identified no differences between supplementing with BA or SB separately (F = 0.58; p = 0.57). Combining BA and SB improved exercise performance, however, there was no benefit in taking these supplements individually. (AU)

• Processo FAPESP: 19/22249-7 - Efeitos da suplementação de beta-alanina e bicarbonato de sódio no desempenho do CrossFit
• Beneficiário: André Guedes da Silva
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 20/12036-3 - A influência do polimorfismo CYP1A2 sobre as respostas fisiológicas e de desempenho após a suplementação aguda de cafeína
• Beneficiário: Gabriel Henrique Castanho Barreto
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto
• Processo FAPESP: 21/06836-0 - Placebo em esporte e exercício: prevalência, condicionamento e placebo aberto
• Beneficiário: Bryan Saunders
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores - Fase 2