| Texto completo | |
| Autor(es): Mostrar menos - |
Loubet Filho, Paulo Sergio
;
Melo, Julia de Arruda
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Baptista, Rafaela Carvalho
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de Lima, Beatriz Gomes Tavarez
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Reguengo, Livia Mateus
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Falk, Renata Bolzan
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Wagner, Roger
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Bogusz Junior, Stanislau
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dos Santos, Elisvania Freitas
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Cazarin, Cinthia Bau Betim
;
Marostica Junior, Mario Roberto
Número total de Autores: 11
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| Tipo de documento: | Artigo Científico |
| Fonte: | Journal of Functional Foods; v. 127, p. 11-pg., 2025-03-22. |
| Resumo | |
The consumption of unsaturated fatty acids, dietary fiber, and anthocyanins, mainly found in fruits, are associated with better health status and modulation of gut microbiota. Thus, the aim of this study is the effect of consumption of Brazilian a & ccedil;ai pulp on metabolic disorders associated with obesity and its prebiotic capacity on gut microbiota. Twenty-four male mice were fed with normolipidic and high-fat standard diets, and normolipidic and a high-fat diets with 2 % of a & ccedil;ai pulp for 13 weeks. The proximal composition, bioactive compounds, and fatty acids composition of a & ccedil;ai pulp was evaluated. For metabolic analysis body composition (whole and adipose weight), glucose metabolism (glucose and insulin tolerance tests), lipids excretion (cholesterol fecal content), and gut microbiota and metabolites (composition and short-chain fatty acids- SCFA) were assessed and compared statistically. The a & ccedil;ai is a fruit source of monounsaturated acids, fibers and anthocyanin with high antioxidant power. Its intake increased weight gain and adipose tissue (except mesenteric adipose tissue) and did not impact on glucose metabolism. A & ccedil;ai intake increased cholesterol fecal excretion associated with a balanced diet, and increased SCFA production in both diet types, indicating that a it might favor the modulation of certain gut bacteria phylum and genera responsible for the SCFA production, such as Actinobacteria, Patescibacteria, Firmicutes, and Akkermansia, Faecalibaculum, Bifidobacteria, Lactobacilli. The 2 % a & ccedil;ai intake was not able to modulated positively the metabolic disorders and gut microbiota in the observed conditions. (AU) | |
| Processo FAPESP: | 15/50333-1 - Cobra: nova plataforma de descoberta de compostos para identificação rápida e de baixo custo de bioativo com efeitos benéficos originários de plantas brasileiras |
| Beneficiário: | Glaucia Maria Pastore |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 15/13320-9 - Efeito do azeite da polpa e do chá das folhas do abacate da variedade Hass associado à atividade física no tratamento da obesidade induzida por dieta hiperlipídica |
| Beneficiário: | Mário Roberto Maróstica Junior |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 18/11069-5 - Ação de berries brasileiras sobre parâmetros metabólicos e desempenho cognitivo de animais obesos |
| Beneficiário: | Mário Roberto Maróstica Junior |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 19/13465-8 - Parceria entre a Universidade de Lund e a Universidade Estadual de Campinas para estudos em alimentos funcionais e dietas na prevenção de doenças cardiometabólicas |
| Beneficiário: | Mário Roberto Maróstica Junior |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |