| Texto completo | |
| Autor(es): |
Lopes, M. Fernanda
;
Gomes, Sandra M.
;
Oliveira, Wanderley P.
;
Santos, Lucia
Número total de Autores: 4
|
| Tipo de documento: | Artigo Científico |
| Fonte: | COSMETICS; v. 12, n. 4, p. 20-pg., 2025-07-28. |
| Resumo | |
The increasing demand for sustainable and safer alternatives in the cosmetic industry has driven the search for multifunctional natural ingredients. Essential oils (EOs), known for their antimicrobial and antioxidant activities, are promising candidates with which to replace synthetic preservatives and antioxidants. This study aimed to evaluate the preservative and antioxidant potential of Lippia origanoides Kunth essential oil, in pure and encapsulated in beta-cyclodextrin form, for cosmetic applications. The EO exhibited strong antioxidant activity, with low IC50 values in DPPH and ABTS assays, and demonstrated antimicrobial efficacy, particularly against Escherichia coli and Staphylococcus aureus. Six cosmetic cream formulations were developed and tested for physicochemical and microbiological stability. Formulations with pure EO maintained high antioxidant performance and remained free of bacterial and fungal contamination over time, outperforming the commercial preservatives. In contrast, formulations with encapsulated EO exhibited delayed antioxidant and antimicrobial activity, indicating gradual release. Overall, Lippia origanoides EO proved to be an effective natural alternative to synthetic preservatives and antioxidants. This approach aligns with the current trend of eco-friendly formulations, offering a sustainable solution by incorporating plant-derived bioactives into cosmetic products. (AU) | |
| Processo FAPESP: | 21/08152-0 - Desafio do uso de medicamentos na piscicultura no contexto One Health: avaliação da eficácia, segurança e análise de risco |
| Beneficiário: | Jonas Augusto Rizzato Paschoal |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 18/26069-0 - Encapsulação de óleos essenciais para uso em formulações farmacêuticas com atividade antimicrobiana |
| Beneficiário: | Wanderley Pereira Oliveira |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |