Neuropsychological Assessment of Current and Past Crack Cocaine Users

Autor(es)

De Oliveira, Lucio Garcia ^[1] ; Barroso, Lucia Pereira ^[2] ; Silveira, Camila Magalhaes ^[3] ; Sanchez, Zila Van Der Meer ^{[4, 5]} ; Ponce, Julio De Carvalho ^[3] ; Vaz, Leonardo Jose ^[4] ; Nappo, Solange Aparecida ^{[4, 5]}

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sch Med, Dept Psychiat, Sao Paulo - Brazil

^[2] Univ Sao Paulo, Dept Stat, Sao Paulo - Brazil

^[3] Ctr Informat Hlth & Alcohol CISA, Sao Paulo - Brazil

^[4] Univ Fed Sao Paulo, Dept Psychobiol, Sao Paulo - Brazil

^[5] Brazilian Ctr Informat Psychotrop Drugs CEBRID, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: SUBSTANCE USE & MISUSE; v. 44, n. 13, p. 1941-1957, 2009.
• Citações Web of Science: 34

Resumo

Background: Cognitive changes due to crack cocaine consumption remain unclear Methods: For clarification, 55 subjects were assigned to three groups: control group, crack cocaine current users, and ex-users. Participants were submitted to Mini-Mental State Examination (MMSE) and tasks evaluating executive functioning and verbal memory Mood state was also measured. Intergroup comparisons were carried out. Results: Control group performance on the MMSE was better than that of users and ex-users. Verbal memory performance for logical memory of users was impaired. Ex-users scored lower on DSST and Trail Making Test (Part B). Conclusion: Chronic crack cocaine use seems to disrupt general cognitive functioning (MMSE), verbal memory, and attentional resources, but findings suggest that some of these effects could be reversed by abstinence. (AU)

• Processo FAPESP: 04/07153-8 - Comportamento e avaliação cognitiva do usuário de crack após uma década de introdução da droga na cidade de São Paulo
• Beneficiário: Solange Aparecida Nappo
• Modalidade de apoio: Auxílio à Pesquisa - Regular