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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Neuropsychological Assessment of Current and Past Crack Cocaine Users

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Author(s):
De Oliveira, Lucio Garcia [1] ; Barroso, Lucia Pereira [2] ; Silveira, Camila Magalhaes [3] ; Sanchez, Zila Van Der Meer [4, 5] ; Ponce, Julio De Carvalho [3] ; Vaz, Leonardo Jose [4] ; Nappo, Solange Aparecida [4, 5]
Total Authors: 7
Affiliation:
[1] Univ Sao Paulo, Sch Med, Dept Psychiat, Sao Paulo - Brazil
[2] Univ Sao Paulo, Dept Stat, Sao Paulo - Brazil
[3] Ctr Informat Hlth & Alcohol CISA, Sao Paulo - Brazil
[4] Univ Fed Sao Paulo, Dept Psychobiol, Sao Paulo - Brazil
[5] Brazilian Ctr Informat Psychotrop Drugs CEBRID, Sao Paulo - Brazil
Total Affiliations: 5
Document type: Journal article
Source: SUBSTANCE USE & MISUSE; v. 44, n. 13, p. 1941-1957, 2009.
Web of Science Citations: 34
Abstract

Background: Cognitive changes due to crack cocaine consumption remain unclear Methods: For clarification, 55 subjects were assigned to three groups: control group, crack cocaine current users, and ex-users. Participants were submitted to Mini-Mental State Examination (MMSE) and tasks evaluating executive functioning and verbal memory Mood state was also measured. Intergroup comparisons were carried out. Results: Control group performance on the MMSE was better than that of users and ex-users. Verbal memory performance for logical memory of users was impaired. Ex-users scored lower on DSST and Trail Making Test (Part B). Conclusion: Chronic crack cocaine use seems to disrupt general cognitive functioning (MMSE), verbal memory, and attentional resources, but findings suggest that some of these effects could be reversed by abstinence. (AU)