Molecular epidemiology of dengue type 3 virus in Brazil and Paraguay, 2002-2004

Autor(es):Mostrar menos -

Aquino, Victor H. ; Anatriello, Elen ; Gonçalves, Paula F. ; Silva, Eliana V. da ; Vasconcelos, Pedro F. C. ; Vieira, Deusylene S. ; Batista, Weber C. ; Bobadilla, Maria L. ; Vazquez, Cynthia ; Moran, Mirian ; Figueiredo, Luiz T. M. ^[11]

• Tipo de documento: Artigo Científico
• Fonte: American Journal of Tropical Medicine and Hygiene; v. 75, n. 4, p. 710-715, 2006.
• Área do conhecimento: Ciências Biológicas - Microbiologia
• Assunto(s): Epidemiologia Vírus de RNA Flavivirus Vírus da dengue

Resumo

We studied the molecular epidemiology of dengue virus type 3 (DENV-3) in Brazil and Paraguay by analyzing the 5' and 3' untranslated regions (5' and 3'UTRs) and the E protein gene of viruses isolated between 2002 and 2004. Both 5' and 3'UTRs were highly conserved. However, the 3'UTR of two isolates from Brazil contained eight nucleotide deletions compared with the remaining 26 viruses. Phylogenetic analyses suggested that DENV-3 was introduced into Brazil from the Caribbean Islands at least twice and into Paraguay from Brazil at least three times. (AU)

• Processo FAPESP: 02/08459-8 - Rede de Diversidade Genética de Vírus (VIRGEN), selecionado para Laboratório L3: projeto: estudos com Hantavirus e vírus da dengue
• Beneficiário: Luiz Tadeu Moraes Figueiredo
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 03/03682-3 - Estudos sobre arboviroses e viroses associadas a roedores
• Beneficiário: Luiz Tadeu Moraes Figueiredo
• Modalidade de apoio: Auxílio à Pesquisa - Temático