Molecular characterization of dengue type 3 isolated in Brazil and Paraguay
| Author(s): Show less - |
Aquino, Victor H.
;
Anatriello, Elen
;
Gonçalves, Paula F.
;
Silva, Eliana V. da
;
Vasconcelos, Pedro F. C.
;
Vieira, Deusylene S.
;
Batista, Weber C.
;
Bobadilla, Maria L.
;
Vazquez, Cynthia
;
Moran, Mirian
;
Figueiredo, Luiz T. M.
[11]
Total Authors: 11
|
| Document type: | Journal article |
| Source: | American Journal of Tropical Medicine and Hygiene; v. 75, n. 4, p. 710-715, 2006. |
| Field of knowledge: | Biological Sciences - Microbiology |
| Abstract | |
We studied the molecular epidemiology of dengue virus type 3 (DENV-3) in Brazil and Paraguay by analyzing the 5' and 3' untranslated regions (5' and 3'UTRs) and the E protein gene of viruses isolated between 2002 and 2004. Both 5' and 3'UTRs were highly conserved. However, the 3'UTR of two isolates from Brazil contained eight nucleotide deletions compared with the remaining 26 viruses. Phylogenetic analyses suggested that DENV-3 was introduced into Brazil from the Caribbean Islands at least twice and into Paraguay from Brazil at least three times. (AU) | |
| FAPESP's process: | 03/03682-3 - Study on Brazilian arboviruses and rodent related viruses |
| Grantee: | Luiz Tadeu Moraes Figueiredo |
| Support type: | Research Projects - Thematic Grants |