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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Brazilian nut consumption improves selenium status and glutathione peroxidase activity and reduces atherogenic risk in obese women

Texto completo
Autor(es):
Cominetti, Cristiane [1] ; de Bortoli, Maritsa C. [2] ; Garrido, Jr., Arthur B. [3] ; Cozzolino, Silvia M. F. [2]
Número total de Autores: 4
Afiliação do(s) autor(es):
[1] Univ Fed Goias, Fac Nutr, Goiania, Go - Brazil
[2] Univ Sao Paulo, Fac Pharmaceut Sci, Dept Food & Expt Nutr, Sao Paulo - Brazil
[3] Univ Sao Paulo, Fac Med, Dept Gastroenterol, Sao Paulo - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: Nutrition Research; v. 32, n. 6, p. 403-407, JUN 2012.
Citações Web of Science: 36
Resumo

Studies have shown that there are inverse relationships between nut consumption and the reduction of cardiovascular risk. This study tested the hypothesis that daily consumption of Brazilian nuts would have a positive effect upon selenium (Se) status, erythrocyte glutathione peroxidase activity, lipid profile, and atherogenic risk in severely obese women. Thirty-seven severely obese women each consumed 1 Brazilian nut a day (290 mu g of Se a day) for 8 weeks. Blood Se concentrations, total erythrocyte glutathione peroxidase activity, lipid profile, and Castelli I and H indexes were evaluated before and after the nuts consumption. All the patients were Se deficient at baseline; this deficiency was remedied by the consumption of the Brazilian nut (P < .0001). The intake of Brazilian nuts promoted a significant increase in high-density lipoprotein cholesterol concentrations (P < .00001), which then resulted in a significant improvement of the Castelli I (P < .0002) and II (P < .0004) indexes. This study shows that obese people who implement daily consumption of Brazilian nuts can improve both Se status and lipid profile, especially high-density lipoprotein cholesterol levels, thereby reducing cardiovascular risks. (C) 2012 Published by Elsevier Inc. (AU)

Processo FAPESP: 07/50533-4 - Efeitos da suplementacao com castanha-do-brasil (bertholletia excelsa h.b.k.) sobre o estresse oxidativo em mulheres obesas e sua relacao com o polimorfismo pro 198leu no gene da glutationa peroxidade 1.
Beneficiário:Silvia Maria Franciscato Cozzolino
Modalidade de apoio: Auxílio à Pesquisa - Regular