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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Dietary omega-3 fatty acid and omega-3: omega-6 fatty acid ratio predict improvement in glucose disturbances in Japanese Brazilians

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Autor(es):
Sartorelli, Daniela S. [1] ; Damiao, Renata [2] ; Chaim, Rita [3] ; Hirai, Amelia [2] ; Gimeno, Suely G. A. [2] ; Ferreira, Sandra R. G. [4] ; Gr, Japanese Brazilian Diabet Study
Número total de Autores: 7
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Dept Social Med, Sch Med Ribeirao Preto, Sao Paulo - Brazil
[2] Univ Fed Sao Paulo, Dept Prevent Med, Sao Paulo - Brazil
[3] Univ Sagiado Coracao, Dept Nutr, Sao Paulo - Brazil
[4] Univ Sao Paulo, Dept Nutr, Sch Publ Hlth, Sao Paulo - Brazil
Número total de Afiliações: 4
Tipo de documento: Artigo Científico
Fonte: NUTRITION; v. 26, n. 2, p. 184-191, FEB 2010.
Citações Web of Science: 10
Resumo

Objective: We investigated whether lifestyle-induced changes in dietary fat quality are related to Improvements on glucose metabolism disturbances in Japanese Brazilians at high risk of type 2 diabetes Methods: One hundred forty-eight first- and second-generation subjects with impaired glucose tolerance or impaired fasting glycemia who attended a lifestyle intervention program for 12 mo were studied in the city of Bauru. State of Sao Paulo, Brazil Dietary fatty acid intakes at baseline and after 12 mo were estimated using three 24-h recalls. The effect of dietary fat intake on glucose metabolism was investigated by multiple logistic regression models Results: At baseline, mean standard deviation age and body mass index were 60 II y and 25 5 4.2 kg/m2, respectively After 12 mo. 92 subjects had normal plasma glucose levels and 56 remained in prediabetic conditions. Using logistic regression models adjusted for age, gender, generation, basal intake of explanatory nutrient, energy intake, physical activity, and waist circumference, the odds ratios (95% confidence intervals) for reversion to normoglycemia were 3 14 (1 22-8 10) in the second wrote of total w-3 fatty acid, 4 26 (1.34-13 57) in the second tunic of eicosapentaenoic acid, and 280 (1 10-7.10) in the second tertile of linolenic acid. Similarly. subjects in the highest wrote of w-3.w-6 fatty acid ratio showed a higher chance of improving glucose disturbances (2 51, 1.01-6.37) Conclusions: Our findings support the evidence of an independent protective effect of omega-3 fatty acid and of a higher omega-3:omega-6 fatty acid ratio on the glucose metabolism of high-risk individuals (C) 2010 Elsevier Inc All rights reserved. (AU)

Processo FAPESP: 05/59178-7 - Estudo de diabetes e doenças associadas na população nipo-brasileira de Bauru: impacto da intervenção no estilo de vida sobre o perfil metabólico e inflamatório de indivíduos de alto risco para a síndrome metabólica
Beneficiário:Suely Godoy Agostinho Gimeno
Modalidade de apoio: Auxílio à Pesquisa - Regular
Processo FAPESP: 05/60290-6 - Impacto da intervencao nutricional sobre os habitos alimentares em individuos com sindrome metabolica.
Beneficiário:Renata Damiao
Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado