Bovine Peritoneum Protection Role on Intestinal Adhesions to a Vascular Graft: A Morphological Analysis

Autor(es)

Uema, Rogerio Takeyoshi ^[1] ; Sassoli Fazan, Valeria Paula ^[1] ; Cherri, Jesualdo ^[1] ; Piccinato, Carlos Eli ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sch Med Ribeirao Preto, Dept Surg & Anat, BR-14049900 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: International Journal of Morphology; v. 26, n. 2, p. 269-274, JUN 2008.
• Citações Web of Science: 0

Resumo

The present study aimed to experimentally evaluate the protection role of glycerin preserved bovine peritoneum (BP) against intestinal adhesions to a vascular graft. Experiments were performed on 24 adult rabbits, randomly dived into two groups. All animals were submitted to a vascular graft over the infra-renal aorta and vena cava. Group I (12 animals) was submitted to a BP patch on the retroperitoneal opening, between the vascular prosthetic graft and the intestinal loops. Group II (12 animals) had the retroperitoneal opening sutured. After 7, 14, 28 and 60 days, 3 animals of each group were randomly killed and the retro peritoneum, with or without the BP patch, was removed for histological analysis. The histological analysis showed that the BP stimulated a moderate to intense inflammatory reaction at the beginning of the experiments and on the 60-day evaluation, the inflammatory reaction was mild, limited to the BP border with its histological structure preserved. In conclusion, the BP is a safe and cheap interposition material to be used between vascular grafts and intestinal loops, presenting a protection role against adhesions between them. (AU)

• Processo FAPESP: 06/03200-7 - Estudo morfológico e morfométrico do nervo sural de ratos normotensos, espontaneamente hipertensos (SHR) e espontaneamente hipertensos com diabete induzido experimentalmente
• Beneficiário: Valéria Paula Sassoli Fazan
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 04/09139-2 - Estudos morfofuncionais e morfométricos do sistema nervoso central e periférico e do sistema cardiovascular, envolvidos na regulação neuro-humoral de funções neurovegetativas e comportamentais
• Beneficiário: Helio Cesar Salgado
• Modalidade de apoio: Auxílio à Pesquisa - Programa Equipamentos Multiusuários