| Texto completo | |
| Autor(es): |
Correa, Telma A. F.
[1]
;
Rogero, Marcelo M.
[1]
;
Mioto, Bruno M.
[2]
;
Tarasoutchi, Daniela
[2]
;
Tuda, Vera L.
[2]
;
Cesar, Luiz A. M.
[2]
;
Torres, Elizabeth A. F. S.
[1]
Número total de Autores: 7
|
| Afiliação do(s) autor(es): | [1] Univ Sao Paulo, Sch Publ Hlth, Dept Nutr, Sao Paulo - Brazil
[2] Univ Sao Paulo, Sch Med, Heart Inst InCor, Sao Paulo - Brazil
Número total de Afiliações: 2
|
| Tipo de documento: | Artigo Científico |
| Fonte: | NUTRITION; v. 29, n. 7-8, p. 977-981, JUL-AUG 2013. |
| Citações Web of Science: | 24 |
| Resumo | |
Objective: The aim of this study was to compare the effects of medium light roast (MLR) and medium roast (MR) paper-filtered coffee on cardiovascular risk factors in healthy volunteers. Methods: This randomized crossover trial compared the effects of consuming three or four cups (150 mL) of MLR or MR coffee per day for 4 wk in 20 healthy volunteers. Plasma lipids, lipoprotein(a) (Lp{[}a]), total homocysteine, and endothelial dysfunction-related inflammation biomarkers, serum glycemic biomarkers, and blood pressure were measured at baseline and after each intervention. Results: Both roasts increased plasma total cholesterol, low-density lipoprotein-cholesterol, and soluble vascular cell adhesion molecule-1 (sVCAM-1) concentrations (10%, 12%, and 18% for MLR; 12%, 14%, and 14% for MR, respectively) (P < 0.05). MR also increased high-density lipoportein-cholesterol concentration by 7% (P = 0.003). Plasma fibrinogen concentration increased 8% after MR intake (P = 0.01), and soluble E-selectin increased 12% after MLR intake (P = 0.02). No changes were observed for Lp(a), total homocysteine, glycemic biomarkers, and blood pressure. Conclusion: Moderate paper-filtered coffee consumption may have an undesirable effect on plasma cholesterol and inflammation biomarkers in healthy individuals regardless of its antioxidant content. (C) 2013 Elsevier Inc. All rights reserved. (AU) | |
| Processo FAPESP: | 08/10933-6 - Estudo da ação antioxidante e dos efeitos dos compostos bioativos do café na prevenção de doenças crônicas não transmissíveis: dislipidemia, diabetes mellitus tipo 2 e hipertensão arterial |
| Beneficiário: | Telma Angelina Faraldo Corrêa |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |
| Processo FAPESP: | 09/05792-7 - Estudo da ação antioxidante e dos efeitos dos compostos bioativos do café sobre o metabolismo glico-lipídico e pressão arterial |
| Beneficiário: | Elizabeth Aparecida Ferraz da Silva Torres |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |