Impact of fat distribution on metabolic, cardiovascular and symptomatic aspects in postmenopausal women

Autor(es)

Paolillo, Fernanda Rossi ^{[1, 2, 3]} ; Milan, Juliana Cristina ^[4] ; Paolillo, Alessandra Rossi ^[5] ; Brasileiro Lopes, Sergio Luiz ^[6] ; Kurachi, Cristina ^{[2, 3]} ; Bagnato, Vanderlei Salvador ^{[2, 3]} ; Borghi-Silva, Audrey ^[4]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, BR-13560970 Sao Carlos, SP - Brazil

^[2] Univ Sao Paulo, Opt Grp, IFSC, BR-13560970 Sao Carlos, SP - Brazil

^[3] Univ Fed Sao Carlos, Biotechnol Program, BR-13560 Sao Carlos, SP - Brazil

^[4] Univ Fed Sao Carlos, Dept Phys Therapy, Cardiopulm Physiotherapy Lab, BR-13565905 Sao Carlos, SP - Brazil

^[5] Univ Sao Paulo, Bioengineer Program, BR-13560970 Sao Carlos, SP - Brazil

^[6] Univ Fed Sao Carlos, Dept Med, BR-13565905 Sao Carlos, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: International Journal of Diabetes in Developing Countries; v. 34, n. 1, p. 32-39, MAR 2014.
• Citações Web of Science: 2

Resumo

The aim of this study was to investigate the anthropometric, metabolic, cardiovascular and symptomatic profile in gynoid and android postmenopausal women. Forty five postmenopausal women aged 50 to 60 years were divided into two groups according to fat distribution {[}waist-to-hip ratio (WHR)]: gynoid group (WHR between 0.68 and 0.8; N = 13) and android group (WHR > 0.8; N = 32). Body composition, skinfold thickness, serum/plasma estradiol, creatinine, urea, lipid profile, glucose and insulin, maximal exercise testing and menopause rating scale (MRS) were evaluated. The android group when compared to the gynoid group showed (P < 0.05): (i) higher values of body mass, BMI, waist circumference, body fat, lean mass and skinfold thickness; (ii) higher values of estradiol, triglycerides, very low-density lipoprotein (VLDL) and insulin levels with lower insulin sensitivity (%S) and greater insulin resistance (%IR) index; (iii) higher blood pressure (BP) during rest and lower maximal heart rate (HRmax) during maximal exercise testing and; (iv) higher scores of the somatic and urogenital-sexual symptoms. This study suggests that android postmenopausal women develop features that can lead to metabolic syndrome (MetS) and future cardiovascular disease (CVD), and these women may present higher scores of somatic and urogenital-sexual symptoms. (AU)

• Processo FAPESP: 09/01842-0 - Análise dos ajustes centrais e metabólicos periféricos durante o exercício físico dinâmico versus resistido em pacientes com DAC: efeitos de um programa de treinamento resistido baseado na determinação do limiar anaeróbio por diferentes metodologias
• Beneficiário: Audrey Borghi Silva
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores
• Processo FAPESP: 98/14270-8 - Centro de Ciências Ópticas e Fotônica
• Beneficiário: Vanderlei Salvador Bagnato
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs