Presence of Vaccine-Derived Newcastle Disease Viruses in Wild Birds

Autor(es):Mostrar menos -

Ayala, Andrea J. ; Dimitrov, Kiril M. ; Becker, Cassidy R. ; Goraichuk, Iryna V. ; Arns, Clarice W. ; Bolotin, Vitaly I. ; Ferreira, Helena L. ; Gerilovych, Anton P. ; Goujgoulova, Gabriela V. ; Martini, Matheus C. ; Muzyka, Denys V. ; Orsi, Maria A. ; Scagion, Guilherme P. ; Silva, Renata K. ; Solodiankin, Olexii S. ; Stegniy, Boris T. ; Miller, Patti J. ; Afonso, Claudio L.

• Tipo de documento: Artigo Científico
• Fonte: PLoS One; v. 11, n. 9 SEP 14 2016.
• Citações Web of Science: 20

Resumo

Our study demonstrates the repeated isolation of vaccine-derived Newcastle disease viruses from different species of wild birds across four continents from 1997 through 2014. The data indicate that at least 17 species from ten avian orders occupying different habitats excrete vaccine-derived Newcastle disease viruses. The most frequently reported isolates were detected among individuals in the order Columbiformes (n = 23), followed in frequency by the order Anseriformes (n = 13). Samples were isolated from both free-ranging (n = 47) and wild birds kept in captivity (n = 7). The number of recovered vaccine-derived viruses corresponded with the most widely utilized vaccines, LaSota (n = 28) and Hitchner B1 (n = 19). Other detected vaccine-derived viruses resembled the PHY-LMV2 and V4 vaccines, with five and two cases, respectively. These results and the ubiquitous and synanthropic nature of wild pigeons highlight their potential role as indicator species for the presence of Newcastle disease virus of low virulence in the environment. The reverse spillover of live agents from domestic animals to wildlife as a result of the expansion of livestock industries employing massive amounts of live virus vaccines represent an underappreciated and poorly studied effect of human activity on wildlife. (AU)

• Processo FAPESP: 15/11510-5 - Desvendando as interações patógeno-hospedeiro e patógeno-patógeno utilizando abordagens de metagenômica viral e sequenciamento de última geração
• Beneficiário: Helena Lage Ferreira
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 13/02059-2 - Detecção sorológica, molecular e caracterização dos Paramyxovirus aviários do tipo 1 (classe I e classe II) em aves silvestres
• Beneficiário: Guilherme Pereira Scagion
• Modalidade de apoio: Bolsas no Brasil - Mestrado