The Effect of a Competitive Futsal Matchon T Lymphocyte Surface Receptor Signaling and Functions

Autor(es):Mostrar menos -

Cury-Boaventura, Maria F. ^[1] ; Gorjao, Renata ^[1] ; de Moura, Nivaldo R. ^[1] ; Santos, Vinicius C. ^[1] ; Bortolon, Jose R. ^[1] ; Murata, Gilson M. ^[1] ; Borges, Leandro da Silva ^[1] ; Momesso, Cesar M. ^[1] ; Dermargos, Alexandre ^[2] ; Pithon-Curi, Tania C. ^[1] ; Hatanaka, Elaine ^[1]

Afiliação do(s) autor(es)

^[1] Univ Cruzeiro Sul, Inst Phys Act & Sport Sci, Sao Paulo - Brazil

^[2] Univ Paulista, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: FRONTIERS IN PHYSIOLOGY; v. 9, MAR 15 2018.
• Citações Web of Science: 2

Resumo

In this study, the lymphocyte activation status (surface expression of CD95, CD28, CD25, and CTLA-4), lymphocyte number, lymphocyte subpopulations, lymphocyte necrosis and/or apoptosis, and lymphocyte release of reactive oxygen species (ROS) were investigated in blood samples from 16 futsal athletes before and immediately following a competitive match. Lymphocytes were isolated from the blood samples, and the cellular parameters were assessed by flow cytometry. The futsal match induced lymphocytosis and lymphocyte apoptosis, as indicated by phosphatidylserine externalization, CD95 expression, and DNA fragmentation. Additionally, the competitive match induced the necrotic death of lymphocytes. No differences in the percentage of CD4+ and CD8+ T cells or in the T-helper/suppressor profile between before and immediately after the match were observed. Additionally, after the futsal match, the CD95 and CD28 expression levels were decreased, and the lymphocytes spontaneously released higher levels of ROS. Regardless of the origin, the situation-specific knowledge of lymphocyte behavior obtained herein may facilitate the design of strategies to control the processes that result in infection and tissue injury and that subsequently decrease athletic performance. (AU)

• Processo FAPESP: 08/56105-7 - Instalacao e envolucao do processo inflamatorio em atletas de futsal: estudo em relacao as posicoes taticas
• Beneficiário: Nivaldo Ribeiro de Moura
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 09/06039-0 - Instalação e evolução do processo inflamatório em atletas de futsal: estudo em relação às posições táticas
• Beneficiário: Elaine Hatanaka Dermargos
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 12/20596-2 - Efeito de uma partida de futsal na ativação, função e morte de linfócitos
• Beneficiário: Elaine Hatanaka Dermargos
• Modalidade de apoio: Auxílio à Pesquisa - Regular