| Full text | |
| Author(s): Show less - |
Cury-Boaventura, Maria F.
[1]
;
Gorjao, Renata
[1]
;
de Moura, Nivaldo R.
[1]
;
Santos, Vinicius C.
[1]
;
Bortolon, Jose R.
[1]
;
Murata, Gilson M.
[1]
;
Borges, Leandro da Silva
[1]
;
Momesso, Cesar M.
[1]
;
Dermargos, Alexandre
[2]
;
Pithon-Curi, Tania C.
[1]
;
Hatanaka, Elaine
[1]
Total Authors: 11
|
| Affiliation: | [1] Univ Cruzeiro Sul, Inst Phys Act & Sport Sci, Sao Paulo - Brazil
[2] Univ Paulista, Sao Paulo - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | FRONTIERS IN PHYSIOLOGY; v. 9, MAR 15 2018. |
| Web of Science Citations: | 2 |
| Abstract | |
In this study, the lymphocyte activation status (surface expression of CD95, CD28, CD25, and CTLA-4), lymphocyte number, lymphocyte subpopulations, lymphocyte necrosis and/or apoptosis, and lymphocyte release of reactive oxygen species (ROS) were investigated in blood samples from 16 futsal athletes before and immediately following a competitive match. Lymphocytes were isolated from the blood samples, and the cellular parameters were assessed by flow cytometry. The futsal match induced lymphocytosis and lymphocyte apoptosis, as indicated by phosphatidylserine externalization, CD95 expression, and DNA fragmentation. Additionally, the competitive match induced the necrotic death of lymphocytes. No differences in the percentage of CD4+ and CD8+ T cells or in the T-helper/suppressor profile between before and immediately after the match were observed. Additionally, after the futsal match, the CD95 and CD28 expression levels were decreased, and the lymphocytes spontaneously released higher levels of ROS. Regardless of the origin, the situation-specific knowledge of lymphocyte behavior obtained herein may facilitate the design of strategies to control the processes that result in infection and tissue injury and that subsequently decrease athletic performance. (AU) | |
| FAPESP's process: | 09/06039-0 - Installation and evolution of inflammation in a Futsal athletes in relation to the tactical positions |
| Grantee: | Elaine Hatanaka Dermargos |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 12/20596-2 - Effect of a futsal match on lymphocyte activation, function and death |
| Grantee: | Elaine Hatanaka Dermargos |
| Support Opportunities: | Regular Research Grants |