Biological activity of 7 beta-acetoxywithanolide D isolated from Acnistus arborescens

Autor(es)

Marciano Correa, Joze Aparecida ^[1] ; Fortkamp, Diana ^[1] ; da Silva, Camila Furtunato ^[2] ; Rocha, Flavio ^[1] ; Gomes, Luiz Humberto ^[3] ; Roncato Duarte, Keila Maria ^[4] ; Ferreira, Antonio Gilberto ^[3] ; de Lira, Simone Possedente ^[5]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Programa Posgrad Microbiol Agr, Escola Super Agr Luiz de Queiroz, Dept Ciencias Exatas, Piracicaba, SP - Brazil

^[2] Univ Sao Paulo, ESALQ, Dept Ciencias Exatas, Curso Grad Ciencias Alimentos, Piracicaba, SP - Brazil

^[3] Univ Sao Paulo, ESALQ, Dept Ciencias Exatas, Piracicaba, SP - Brazil

^[4] APTA Reg Polo Ctr Sul, Unidade Pesquisa Tiete, Tiete, SP - Brazil

^[5] Univ Fed Sao Carlos, Dept Quim, Sao Carlos, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: SEMINA-CIENCIAS AGRARIAS; v. 39, n. 6, p. 2835-2841, NOV-DEC 2018.
• Citações Web of Science: 0

Resumo

Many oomycete species are plant pathogens and are responsible for causing significant losses in agriculture. Currently, plant pathogen control is carried out by chemical, biological and physical methods. However, due to the development of resistance to these methods by some pathogens, it is imperative that alternative methods are developed. Brazilian biodiversity is well-known for its species richness and is considered a promising source of natural products. Among the vascular plants, the family Solanaceae A. Juss. (Solanaceac) is considered one of the largest, with distributions across all tropical and temperate regions of the world. The Solanaceae family presents a high diversity of species of economic importance as sources of food, medicinal and ornamental properties. Plants of this family are sources of secondary metabolites of various chemical classes that possess potential diverse applications. Therefore, chemical and biological investigations of these compounds are extremely important as they present alternatives for their potential use in the control of plant pathogens. Here, we report for the first time, the biological activity of 7 beta-acetoxywithanolide D, a compound isolated from Acnistus arborescens, against the oomycete Phytophthora cinnamomi. With these results, we emphasize the importance of such studies on plant secondary metabolites, which may present coadjuvant options in the control of plant pathogens. (AU)

• Processo FAPESP: 12/02861-0 - Bioprospecção de solanáceas (Solanaceae) com atividade fungitóxica à Moniliophthora perniciosa
• Beneficiário: Flávio Rocha
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 13/50228-8 - Componentes da biodiversidade, e seus caracteres metabólicos, de ilhas do Brasil: uma abordagem integrada
• Beneficiário: Roberto Gomes de Souza Berlinck
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOTA - Temático
• Processo FAPESP: 14/15760-3 - Potencial biotecnológico de metabólitos secundários de plantas e fungos endofíticos
• Beneficiário: Simone Possedente de Lira
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 11/09349-0 - Investigação química e biológica de extrato de duas espécies da familia Solanaceae com atividade antifúngica para Moniliophthora perniciosa, causador da doença vassoura de bruxa no cacaueiro.
• Beneficiário: Camila Furtunato da Silva
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica