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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Biological activity of 7 beta-acetoxywithanolide D isolated from Acnistus arborescens

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Marciano Correa, Joze Aparecida [1] ; Fortkamp, Diana [1] ; da Silva, Camila Furtunato [2] ; Rocha, Flavio [1] ; Gomes, Luiz Humberto [3] ; Roncato Duarte, Keila Maria [4] ; Ferreira, Antonio Gilberto [3] ; de Lira, Simone Possedente [5]
Total Authors: 8
[1] Univ Sao Paulo, Programa Posgrad Microbiol Agr, Escola Super Agr Luiz de Queiroz, Dept Ciencias Exatas, Piracicaba, SP - Brazil
[2] Univ Sao Paulo, ESALQ, Dept Ciencias Exatas, Curso Grad Ciencias Alimentos, Piracicaba, SP - Brazil
[3] Univ Sao Paulo, ESALQ, Dept Ciencias Exatas, Piracicaba, SP - Brazil
[4] APTA Reg Polo Ctr Sul, Unidade Pesquisa Tiete, Tiete, SP - Brazil
[5] Univ Fed Sao Carlos, Dept Quim, Sao Carlos, SP - Brazil
Total Affiliations: 5
Document type: Journal article
Source: SEMINA-CIENCIAS AGRARIAS; v. 39, n. 6, p. 2835-2841, NOV-DEC 2018.
Web of Science Citations: 0

Many oomycete species are plant pathogens and are responsible for causing significant losses in agriculture. Currently, plant pathogen control is carried out by chemical, biological and physical methods. However, due to the development of resistance to these methods by some pathogens, it is imperative that alternative methods are developed. Brazilian biodiversity is well-known for its species richness and is considered a promising source of natural products. Among the vascular plants, the family Solanaceae A. Juss. (Solanaceac) is considered one of the largest, with distributions across all tropical and temperate regions of the world. The Solanaceae family presents a high diversity of species of economic importance as sources of food, medicinal and ornamental properties. Plants of this family are sources of secondary metabolites of various chemical classes that possess potential diverse applications. Therefore, chemical and biological investigations of these compounds are extremely important as they present alternatives for their potential use in the control of plant pathogens. Here, we report for the first time, the biological activity of 7 beta-acetoxywithanolide D, a compound isolated from Acnistus arborescens, against the oomycete Phytophthora cinnamomi. With these results, we emphasize the importance of such studies on plant secondary metabolites, which may present coadjuvant options in the control of plant pathogens. (AU)

FAPESP's process: 12/02861-0 - Bioprospection of solanaceous (Solanaceae) with fungitoxic activity against Moniliophthora perniciosa
Grantee:Flávio Rocha
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 13/50228-8 - Biodiversity components, and its metabolic characters, of Brazilian Islands
Grantee:Roberto Gomes de Souza Berlinck
Support type: BIOTA-FAPESP Program - Thematic Grants
FAPESP's process: 14/15760-3 - Biotechnological potential of secondary metabolites from plants and endophytic fungi
Grantee:Simone Possedente de Lira
Support type: Regular Research Grants
FAPESP's process: 11/09349-0 - Chemical and Biological studies of two Solanum species extracts presenting Moniliophthora perniciosa anti-fungi activity (cocoa witches´broom disease)
Grantee:Camila Furtunato da Silva
Support type: Scholarships in Brazil - Scientific Initiation