Bovine Peritoneum Protection Role on Intestinal Adhesions to a Vascular Graft: A Morphological Analysis

Autor(es)

Rogério Takeyoshi Uema ^[1] ; Valéria Paula Sassoli Fazan ^[2] ; Jesualdo Cherri ^[3] ; Carlos Eli Piccinato ^[4]

Afiliação do(s) autor(es)

^[1] University of São Paulo. School of Medicine of Ribeirão Preto. Department of Surgery and Anatomy - Brasil

^[2] University of São Paulo. School of Medicine of Ribeirão Preto. Department of Surgery and Anatomy - Brasil

^[3] University of São Paulo. School of Medicine of Ribeirão Preto. Department of Surgery and Anatomy - Brasil

^[4] University of São Paulo. School of Medicine of Ribeirão Preto. Department of Surgery and Anatomy - Brasil

• Tipo de documento: Artigo Científico
• Fonte: INTERNATIONAL JOURNAL OF MORPHOLOGY; v. 26, n. 2, p. 269-274, 2008-06-00.

Resumo

The present study aimed to experimentally evaluate the protection role of glycerin preserved bovine peritoneum (BP) against intestinal adhesions to a vascular graft. Experiments were performed on 24 adult rabbits, randomly dived into two groups. All animals were submitted to a vascular graft over the infra-renal aorta and vena cava. Group 1(12 animals ) was submitted to a BP patch on the retroperitoneal opening, between the vascular prosthetic graft and the intestinal loops. Group II (12 animals ) had the retroperitoneal opening sutured. After 7, 14, 28 and 60 days, 3 animals of each group were randomly killed and the retro peritoneum, with or without the BPpatch, was removed for histological analysis. The histological analysis showed that the BP stimulated a moderate to intense inflammatory reaction at the beginning of the experiments and on the 60-day evaluation, the inflammatory reaction was mild, limited to the BP border with its histological structure preserved. In conclusión, the BP is a safe and cheap interposition material to be used between vascular grafts and intestinal loops, presenting a protection role against adhesions between them. (AU)

• Processo FAPESP: 06/03200-7 - Estudo morfológico e morfométrico do nervo sural de ratos normotensos, espontaneamente hipertensos (SHR) e espontaneamente hipertensos com diabete induzido experimentalmente
• Beneficiário: Valéria Paula Sassoli Fazan
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 04/09139-2 - Estudos morfofuncionais e morfométricos do sistema nervoso central e periférico e do sistema cardiovascular, envolvidos na regulação neuro-humoral de funções neurovegetativas e comportamentais
• Beneficiário: Helio Cesar Salgado
• Modalidade de apoio: Auxílio à Pesquisa - Programa Equipamentos Multiusuários