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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Bovine Peritoneum Protection Role on Intestinal Adhesions to a Vascular Graft: A Morphological Analysis

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Author(s):
Rogério Takeyoshi Uema [1] ; Valéria Paula Sassoli Fazan [2] ; Jesualdo Cherri [3] ; Carlos Eli Piccinato [4]
Total Authors: 4
Affiliation:
[1] University of São Paulo. School of Medicine of Ribeirão Preto. Department of Surgery and Anatomy - Brasil
[2] University of São Paulo. School of Medicine of Ribeirão Preto. Department of Surgery and Anatomy - Brasil
[3] University of São Paulo. School of Medicine of Ribeirão Preto. Department of Surgery and Anatomy - Brasil
[4] University of São Paulo. School of Medicine of Ribeirão Preto. Department of Surgery and Anatomy - Brasil
Total Affiliations: 4
Document type: Journal article
Source: INTERNATIONAL JOURNAL OF MORPHOLOGY; v. 26, n. 2, p. 269-274, 2008-06-00.
Abstract

The present study aimed to experimentally evaluate the protection role of glycerin preserved bovine peritoneum (BP) against intestinal adhesions to a vascular graft. Experiments were performed on 24 adult rabbits, randomly dived into two groups. All animals were submitted to a vascular graft over the infra-renal aorta and vena cava. Group 1(12 animals ) was submitted to a BP patch on the retroperitoneal opening, between the vascular prosthetic graft and the intestinal loops. Group II (12 animals ) had the retroperitoneal opening sutured. After 7, 14, 28 and 60 days, 3 animals of each group were randomly killed and the retro peritoneum, with or without the BPpatch, was removed for histological analysis. The histological analysis showed that the BP stimulated a moderate to intense inflammatory reaction at the beginning of the experiments and on the 60-day evaluation, the inflammatory reaction was mild, limited to the BP border with its histological structure preserved. In conclusión, the BP is a safe and cheap interposition material to be used between vascular grafts and intestinal loops, presenting a protection role against adhesions between them. (AU)