Busca avançada
Ano de início
Entree
(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Production and characterization of solid lipid microparticles loaded with guarana (Paullinia cupana) seed extract

Texto completo
Autor(es):
Silva, Marluci P. [1] ; Thomazini, Marcelo [1] ; Holkem, Augusto T. [1] ; Pinho, Lorena S. [1] ; Genovese, Maria I. [2] ; Favaro-Trindade, Carmen S. [1]
Número total de Autores: 6
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Fac Zootecnia & Engn Alimentos, Dept Engn Alimentos, Pirassununga, SP - Brazil
[2] Univ Sao Paulo, Fac Ciencias Farmaceut, Dept Alimentos & Nutr Expt, Sao Paulo, SP - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: Food Research International; v. 123, p. 144-152, SEP 2019.
Citações Web of Science: 2
Resumo

Guarana is a native fruit of the Amazon rainforest, which presents high levels of phenolic compounds. However, these bioactive compounds may be unstable in food processing and gastrointestinal conditions. Thus, this work aimed to characterize guarana seed extract (GSE) followed by microencapsulation using a spray-chilling method and with vegetable fat as carrier, as well as to evaluate the particles. Phenolic-rich GSE was produced using 50% (w/w) hydroalcoholic solution and dehydrated by spray drying and lyophilization. Powdered GSE was characterized in relation to its inhibitory activity on digestive enzymes. Solid lipid microparticles (SLM) were evaluated for the retention of bioactive compounds and the release profile of phenolic compounds in simulated gastrointestinal conditions. Powdered GSE showed anti-obesity potential due to the high inhibitory activity of lipase. Regarding the retention of phenolic compounds, at least 75% were detected after 90 days at 25 degrees C in SLM. Moreover, SLM loaded with 7.5% GSE released approximately 99% of phenolic compounds in simulated gastrointestinal conditions. These results show the efficiency of spray chilling for protection and release of phenolic compounds from GSE, allowing future application in food. (AU)

Processo FAPESP: 16/24895-5 - Coencapsulação dos extratos do guaraná (Paullinia cupana) e probióticos
Beneficiário:Marluci Palazzolli da Silva
Linha de fomento: Bolsas no Brasil - Doutorado
Processo FAPESP: 16/24916-2 - Obtenção, encapsulação e aplicação de extrato de carotenoides obtido da casca do guaraná (Paullinia cupana)
Beneficiário:Lorena Silva Pinho
Linha de fomento: Bolsas no Brasil - Doutorado
Processo FAPESP: 18/05315-3 - Propriedades quimiopreventivas de extratos de mirtilos, jabuticabas e canela isolados ou combinados com probióticos
Beneficiário:Augusto Tasch Holkem
Linha de fomento: Bolsas no Exterior - Estágio de Pesquisa - Doutorado
Processo FAPESP: 15/19375-0 - Coencapsulação dos probióticos e extrato rico em proantocianidinas obtido da canela (Cinnamomum zeylanicum Blume)
Beneficiário:Augusto Tasch Holkem
Linha de fomento: Bolsas no Brasil - Doutorado