Effects of Blood Transfusion Sets on Red Blood Cell Hemolysis

Autor(es)

Pardo, Larissa Perez ^{[1, 2]} ; Kusahara, Denise Miyuki ^[3] ; de Oliveira Pires, Maria Paula ^{[3, 2, 4]} ; Silva Nani, Luiz Augusto ^[5] ; Machado Avelar, Ariane Ferreira ^[3] ; Sorgini Peterlini, Maria Angelica ^[3] ; Goncalves Pedreira, Mavilde Luz ^[3]

Afiliação do(s) autor(es)

^[1] Univ Fed Sao Paulo, Paulista Sch Nursing, Sao Paulo, SP - Brazil

^[2] Univ Paulista, Nursing, Sao Paulo, SP - Brazil

^[3] Univ Fed Sao Paulo, Sao Paulo, SP - Brazil

^[4] Griffith Univ, Alliance Vasc Access Teaching & Res AVATAR Grp, Menzies Hlth Inst Queensland, Brisbane, Qld - Australia

^[5] Colsan Blood Collect Assoc, Sao Paulo, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF INFUSION NURSING; v. 42, n. 6, p. 303-310, NOV-DEC 2019.
• Citações Web of Science: 0

Resumo

This experimental randomized study compared the effects of macrodrop and microdrop blood transfusion sets on red blood cell (RBC) hemolysis. Twenty units of packed RBCs from different donors were infused through 48 infusion sets from 2 manufacturers at infusion rates of 10 and 100 mL/h. Pre- and postinfusion analysis was performed to determine total hemoglobin (g/dL), hematocrit (%), free hemoglobin (g/dL), potassium (mmol/L), haptoglobin (g/L), and degree of hemolysis (%). The results demonstrated that the level of free hemoglobin (P < .001) and degree of hemolysis (P < .001) increased postinfusion. A higher degree of hemolysis was noted when the RBCs were infused at a rate of 10 mL/h through a microdrop blood transfusion set. (AU)

• Processo FAPESP: 12/25284-9 - Estudo de biomarcadores de hemólise de concentrados de hemácias administrados por dispositivos de infusão eletrônicos e manuais
• Beneficiário: Mavilde da Luz Gonçalves Pedreira
• Modalidade de apoio: Auxílio à Pesquisa - Regular