Advanced search
Start date
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effects of Blood Transfusion Sets on Red Blood Cell Hemolysis

Full text
Pardo, Larissa Perez [1, 2] ; Kusahara, Denise Miyuki [3] ; de Oliveira Pires, Maria Paula [3, 2, 4] ; Silva Nani, Luiz Augusto [5] ; Machado Avelar, Ariane Ferreira [3] ; Sorgini Peterlini, Maria Angelica [3] ; Goncalves Pedreira, Mavilde Luz [3]
Total Authors: 7
[1] Univ Fed Sao Paulo, Paulista Sch Nursing, Sao Paulo, SP - Brazil
[2] Univ Paulista, Nursing, Sao Paulo, SP - Brazil
[3] Univ Fed Sao Paulo, Sao Paulo, SP - Brazil
[4] Griffith Univ, Alliance Vasc Access Teaching & Res AVATAR Grp, Menzies Hlth Inst Queensland, Brisbane, Qld - Australia
[5] Colsan Blood Collect Assoc, Sao Paulo, SP - Brazil
Total Affiliations: 5
Document type: Journal article
Source: JOURNAL OF INFUSION NURSING; v. 42, n. 6, p. 303-310, NOV-DEC 2019.
Web of Science Citations: 0

This experimental randomized study compared the effects of macrodrop and microdrop blood transfusion sets on red blood cell (RBC) hemolysis. Twenty units of packed RBCs from different donors were infused through 48 infusion sets from 2 manufacturers at infusion rates of 10 and 100 mL/h. Pre- and postinfusion analysis was performed to determine total hemoglobin (g/dL), hematocrit (%), free hemoglobin (g/dL), potassium (mmol/L), haptoglobin (g/L), and degree of hemolysis (%). The results demonstrated that the level of free hemoglobin (P < .001) and degree of hemolysis (P < .001) increased postinfusion. A higher degree of hemolysis was noted when the RBCs were infused at a rate of 10 mL/h through a microdrop blood transfusion set. (AU)

FAPESP's process: 12/25284-9 - Hemolysis biomarkers study of red blood cells infused by manual and eletronic infusion devices
Grantee:Mavilde da Luz Gonçalves Pedreira
Support type: Regular Research Grants