Production of resveratrol loaded alginate aerogel: Characterization, mathematical modeling, and study of impregnation

Autor(es)

dos Santos, Philipe ^[1] ; Vigano, Juliane ^[1] ; Furtado, Guilherme de Figueiredo ^[1] ; Cunha, Rosiane Lopes ^[1] ; Hubinger, Miriam Dupas ^[1] ; Rezende, Camila Alves ^[2] ; Martinez, Julian ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, UNICAMP, Food Engn Dept, Sch Food Engn, BR-13083862 Campinas, SP - Brazil

^[2] Univ Estadual Campinas, UNICAMP, Inst Chem, BR-13083862 Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF SUPERCRITICAL FLUIDS; v. 163, SEP 1 2020.
• Citações Web of Science: 0

Resumo

Biodegradable polymers have been studied for the production of aerogels, which are specially useful in impregnation processes of target compounds for food and pharmaceutical applications. The aim of this study was to investigate different aspects in the production of alginate aerogels, including the formation of beads (different sizes); the drying kinetics of aerogel in supercritical CO2; and the loading of a resveratrol by the indirect wet impregnation method. High surface area and pore volume (484 m(2)/g and 0.70 cc/g) were obtained by the atomization with solvent exchange gradient, while the aerogels produced by dripping without gradient showed surface area of 381 m(2)/g and pore volume of 0.68 cc/g. Sodium alginate aerogel showed to be an appropriate material to load high amounts of resveratrol, with a loading capacity directly correlated to the concentration of resveratrol solution. Wet impregnation and supercritical drying can be presented as feasible techniques to load bioactive compounds. (C) 2020 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 16/02007-0 - Aplicação de tecnologia supercrítica para obtenção de partículas de aerogel carreadoras de extrato fenólico do bagaço de maracujá amarelo
• Beneficiário: Juliane Viganó
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 15/11932-7 - Integração de processos de extração a alta pressão com operações de separação para o aproveitamento de subprodutos do processamento de frutas
• Beneficiário: Julian Martínez
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 17/23670-2 - Biorrefinaria para aproveitamento de subprodutos do processamento de maracujá com tecnologias de alta pressão
• Beneficiário: Julian Martínez
• Modalidade de apoio: Auxílio à Pesquisa - Regular