Effect of Duodenogastric Reflux on Dental Enamel

Autor(es)

Faraoni, Juliana Jendiroba ^[1] ; de Andrade, Julia Barone ^[1] ; Machado de Matos, Lais Lopes ^[1] ; Palma-Dibb, Regina Guenka ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Dept Restorat Dent, Sch Dent Ribeirao Preto, Ribeirao Preto, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: ORAL HEALTH & PREVENTIVE DENTISTRY; v. 18, n. 4, p. 701-706, JUL-AUG 2020.
• Citações Web of Science: 0

Resumo

Purpose: To evaluate the effects of stomach and duodenal fluid on enamel surfaces, simulating the action of refluxed liquid in patients with duodenogastric reflux. Methods and Materials: Forty bovine incisors were used to obtain enamel fragments. Only half of the enamel surface was exposed to erosive challenges; the samples were then randomly divided into the following four groups (n = 10): G1: HCl; G2: HCl + pepsin: G3: HCl + ox bile + NaHCO3; and G4: HCl + pancreatin + NaHCO3. The specimens were placed in 37 degrees C solutions, six times per day, for 20 s, over a period of 5 days and then analysed for morphology, surface roughness and the step formed on the dental enamel using confocal laser microscopy. The data were analysed using the Kruskal-Wallis and Dunn's test (p <0.05). Results: Both analyses revealed a higher step and surface roughness for the G3 group (5.6 mu m +/- 1.69, 2.2 mu m +/- 1.61), which were statistically significant compared with the 01 and G2 groups (3.9 mu m +/- 1.5 mu m; 1.0 mu m +/- 0.18; 3.7 mu m +/- 1.45; and 0.9 mu m +/- 0.12) (p <0.05); only the step in the G4 group (4.9 mu m +/- 1.8 mu m) was similar to that of the G3 group (p >0.05). Morphological analysis showed greater structural loss in the G3 and G4 groups. Conclusions: Bile and pancreatin, in combination with hydrochloric acid, may promote a greater loss of structure, increased surface roughness and loss of enamel prismatic anatomy. (AU)

• Processo FAPESP: 13/01413-7 - Influência do refluxo duodeno-gástrico no esmalte dental
• Beneficiário: Julia Barone de Andrade
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 11/12901-7 - Análise in vitro e in situ da erosão dental e de métodos de prevenção em pacientes portadores da doença do refluxo gastroesofágico
• Beneficiário: Regina Guenka Palma-Dibb
• Modalidade de apoio: Auxílio à Pesquisa - Regular