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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effect of Duodenogastric Reflux on Dental Enamel

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Author(s):
Faraoni, Juliana Jendiroba [1] ; de Andrade, Julia Barone [1] ; Machado de Matos, Lais Lopes [1] ; Palma-Dibb, Regina Guenka [1]
Total Authors: 4
Affiliation:
[1] Univ Sao Paulo, Dept Restorat Dent, Sch Dent Ribeirao Preto, Ribeirao Preto, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: ORAL HEALTH & PREVENTIVE DENTISTRY; v. 18, n. 4, p. 701-706, JUL-AUG 2020.
Web of Science Citations: 0
Abstract

Purpose: To evaluate the effects of stomach and duodenal fluid on enamel surfaces, simulating the action of refluxed liquid in patients with duodenogastric reflux. Methods and Materials: Forty bovine incisors were used to obtain enamel fragments. Only half of the enamel surface was exposed to erosive challenges; the samples were then randomly divided into the following four groups (n = 10): G1: HCl; G2: HCl + pepsin: G3: HCl + ox bile + NaHCO3; and G4: HCl + pancreatin + NaHCO3. The specimens were placed in 37 degrees C solutions, six times per day, for 20 s, over a period of 5 days and then analysed for morphology, surface roughness and the step formed on the dental enamel using confocal laser microscopy. The data were analysed using the Kruskal-Wallis and Dunn's test (p <0.05). Results: Both analyses revealed a higher step and surface roughness for the G3 group (5.6 mu m +/- 1.69, 2.2 mu m +/- 1.61), which were statistically significant compared with the 01 and G2 groups (3.9 mu m +/- 1.5 mu m; 1.0 mu m +/- 0.18; 3.7 mu m +/- 1.45; and 0.9 mu m +/- 0.12) (p <0.05); only the step in the G4 group (4.9 mu m +/- 1.8 mu m) was similar to that of the G3 group (p >0.05). Morphological analysis showed greater structural loss in the G3 and G4 groups. Conclusions: Bile and pancreatin, in combination with hydrochloric acid, may promote a greater loss of structure, increased surface roughness and loss of enamel prismatic anatomy. (AU)

FAPESP's process: 13/01413-7 - Influence of duodenogastric reflux on tooth enamel
Grantee:Julia Barone de Andrade
Support Opportunities: Scholarships in Brazil - Master
FAPESP's process: 11/12901-7 - In vitro and in situ analysis of dental erosion and prevention methods in patients with gastroesophageal reflux disease
Grantee:Regina Guenka Palma-Dibb
Support Opportunities: Regular Research Grants