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Influence of duodenogastric reflux on tooth enamel

Grant number: 13/01413-7
Support Opportunities:Scholarships in Brazil - Master
Effective date (Start): June 01, 2013
Effective date (End): February 28, 2015
Field of knowledge:Health Sciences - Dentistry
Principal Investigator:Regina Guenka Palma-Dibb
Grantee:Julia Barone de Andrade
Host Institution: Faculdade de Odontologia de Ribeirão Preto (FORP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil


In patients with duodenogastric reflux, the refluxed liquid is composed of acidic and alkaline substances that may promote structural changes in the dental substrate. Under these circumstances, this study aims to measure the action of this liquid content in the surface enamel. In order to obtain 70 fragments of bovine incisive enamel, dimensions 4x4, there will be initial microhardness analysis using a microhardness tester, for selecting the specimens and subsequently they will have half of the surface isolated with composite resin (control area) the other half will be exposed and will be submitted to erosive challenges, divided into 7 groups (G) 1: control, 2: exposition of hydrochloric acid, 3: Exposure of Ox Bile, 4: Exposure in a mixture of NaHCO3 + HCl (pH 4.5), 5: Exposure in a mixture of NaHCO3 + HCl (pH 5.0), 6: Exposure in a mixture of NaHCO3 + HCl (pH 5.5), 7 : Exposure in a mixture of HCl + NaHCO3 + Ox Bile (pH 7.0). The erosive challenge of group 2 is accomplished by exposing the fragments to a solution of HCl pH 2.0, 6 times a day for 5 days for a time to be determined, in groups 4-7 will be performed preliminary studies to define the solutions concentrations, immersion time and cycling time. The analysis will be in function of wear, surface roughness and microhardness. The data obtained from the tests of wear, surface roughness and microhardness will be analyzed for their distribution, if this is normal will be accomplished ANOVA, otherwise will be conducted nonparametric test. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
FARAONI, JULIANA JENDIROBA; DE ANDRADE, JULIA BARONE; MACHADO DE MATOS, LAIS LOPES; PALMA-DIBB, REGINA GUENKA. Effect of Duodenogastric Reflux on Dental Enamel. ORAL HEALTH & PREVENTIVE DENTISTRY, v. 18, n. 4, p. 701-706, . (13/01413-7, 11/12901-7)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
ANDRADE, Julia Barone de. Effect of duodenalgastric reflux in dental enamel. 2015. Master's Dissertation - Universidade de São Paulo (USP). Faculdade de Odontologia de Ribeirão Preto (PCARP/BC) Ribeirão Preto.

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