Busca avançada
Ano de início
Entree
(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Concentrations of Acute-Phase Proteins in Milk from Cows with Clinical Mastitis Caused by Different Pathogens

Texto completo
Autor(es):
Dalanezi, Felipe M. [1] ; Schmidt, Elizabeth M. S. [2] ; Joaquim, Samea F. [1] ; Guimaraes, Felipe F. [1] ; Guerra, Simoni T. [1] ; Lopes, Bruna C. [1] ; Cerri, Ronaldo L. A. [3] ; Chadwick, Christopher [4] ; Langoni, Helio [1]
Número total de Autores: 9
Afiliação do(s) autor(es):
[1] Sao Paulo State Univ UNESP, Dept Anim Prod & Prevent Vet Med, Fac Med Vet & Anim Sci, BR-18168681 Sao Paulo - Brazil
[2] Sao Paulo State Univ UNESP, Dept Vet Clin Sci, Fac Med Vet & Anim Sci, BR-18168681 Sao Paulo - Brazil
[3] Univ British Columbia, Fac Land & Food Syst, Appl Anim Biol, Vancouver, BC V6T 1Z4 - Canada
[4] Life Diag Inc, W Chester, PA 19380 - USA
Número total de Afiliações: 4
Tipo de documento: Artigo Científico
Fonte: PATHOGENS; v. 9, n. 9 SEP 2020.
Citações Web of Science: 0
Resumo

Among the new diagnostic methods for mastitis detection under development, milk acute-phase proteins (APPs) are receiving special attention. The study aimed to compare the profile of milk APPs from cows with natural clinical mastitis caused by distinct pathogens. The concentrations of haptoglobin (Hp), serum amyloid A (SAA), alpha-1-acid glycoprotein (AGP), and C-reactive protein (CRP) were measured by Spatial Proximity Analyte Reagent Capture Luminescence (SPARCL). Each APP was compared across the pathogens causing mastitis. The APPs differed statistically (p< 0.05) among the pathogens causing udder infection. There were significant and positive correlations among the concentration profile, for each pathogen, in three of four APPs studied. It can be concluded that the pathogen causing mastitis could modify the profile of release of the APPs in milk. The profile of Hp, AGP, and CRP demonstrated significant correlation, indicating that the three APPs are suggested as biomarkers, in milk, for bovine mastitis. (AU)

Processo FAPESP: 15/26055-1 - Influência dos patógenos causadores da mastite clínica nos índices reprodutivos de vacas leiteiras
Beneficiário:Felipe Morales Dalanezi
Modalidade de apoio: Bolsas no Brasil - Doutorado
Processo FAPESP: 15/19688-8 - E. coli, Klebsiella pneumoniae e Enterococcus spp: impacto dos fatores de virulência na mastite bovina e reflexos na saúde pública
Beneficiário:Helio Langoni
Modalidade de apoio: Auxílio à Pesquisa - Temático