The role of selection in the evolution of marine turtles mitogenomes

Autor(es)

da Silva Ramos, Elisa Karen ^[1] ; Freitas, Lucas ^[1] ; Nery, Mariana F. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, Dept Genet Evolucao Microbiol & Imunol, Lab Genom Evolut, Cidade Univ, BR-13083970 Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: SCIENTIFIC REPORTS; v. 10, n. 1 OCT 12 2020.
• Citações Web of Science: 0

Resumo

Sea turtles are the only extant chelonian representatives that inhabit the marine environment. One key to successful colonization of this habitat is the adaptation to different energetic demands. Such energetic requirement is intrinsically related to the mitochondrial ability to generate energy through oxidative phosphorylation (OXPHOS) process. Here, we estimated Testudines phylogenetic relationships from 90 complete chelonian mitochondrial genomes and tested the adaptive evolution of 13 mitochondrial protein-coding genes of sea turtles to determine how natural selection shaped mitochondrial genes of the Chelonioidea clade. Complete mitogenomes showed strong support and resolution, differing at the position of the Chelonioidea clade in comparison to the turtle phylogeny based on nuclear genomic data. Codon models retrieved a relatively increased dN/dS (omega) on three OXPHOS genes for sea turtle lineages. Also, we found evidence of positive selection on at least three codon positions, encoded by NADH dehydrogenase genes (ND4 and ND5). The accelerated evolutionary rates found for sea turtles on COX2, ND1 and CYTB and the molecular footprints of positive selection found on ND4 and ND5 genes may be related to mitochondrial molecular adaptation to stress likely resulted from a more active lifestyle in sea turtles. Our study provides insight into the adaptive evolution of the mtDNA genome in sea turtles and its implications for the molecular mechanism of oxidative phosphorylation. (AU)

• Processo FAPESP: 15/18269-1 - Usando genômica comparativa para entender a evolução convergente de mamíferos: em busca das pegadas moleculares da ocupação do ambiente marinho e fluvial
• Beneficiário: Mariana Freitas Nery
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores
• Processo FAPESP: 17/25058-2 - Evolução adaptativa convergente de genes relacionados à hematofagia em Insecta
• Beneficiário: Lucas Araujo Freitas
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 18/01236-1 - Evolução em mamíferos aquáticos na ocupação de novos ambientes: investigando as pegadas moleculares da colonização do ambiente fluvial com foco no sistema de osmorregulação
• Beneficiário: Elisa Karen da Silva Ramos
• Modalidade de apoio: Bolsas no Brasil - Doutorado