| Full text | |
| Author(s): |
Total Authors: 3
|
| Affiliation: | [1] Univ Estadual Campinas, Dept Genet Evolucao Microbiol & Imunol, Lab Genom Evolut, Cidade Univ, BR-13083970 Campinas, SP - Brazil
Total Affiliations: 1
|
| Document type: | Journal article |
| Source: | SCIENTIFIC REPORTS; v. 10, n. 1 OCT 12 2020. |
| Web of Science Citations: | 0 |
| Abstract | |
Sea turtles are the only extant chelonian representatives that inhabit the marine environment. One key to successful colonization of this habitat is the adaptation to different energetic demands. Such energetic requirement is intrinsically related to the mitochondrial ability to generate energy through oxidative phosphorylation (OXPHOS) process. Here, we estimated Testudines phylogenetic relationships from 90 complete chelonian mitochondrial genomes and tested the adaptive evolution of 13 mitochondrial protein-coding genes of sea turtles to determine how natural selection shaped mitochondrial genes of the Chelonioidea clade. Complete mitogenomes showed strong support and resolution, differing at the position of the Chelonioidea clade in comparison to the turtle phylogeny based on nuclear genomic data. Codon models retrieved a relatively increased dN/dS (omega) on three OXPHOS genes for sea turtle lineages. Also, we found evidence of positive selection on at least three codon positions, encoded by NADH dehydrogenase genes (ND4 and ND5). The accelerated evolutionary rates found for sea turtles on COX2, ND1 and CYTB and the molecular footprints of positive selection found on ND4 and ND5 genes may be related to mitochondrial molecular adaptation to stress likely resulted from a more active lifestyle in sea turtles. Our study provides insight into the adaptive evolution of the mtDNA genome in sea turtles and its implications for the molecular mechanism of oxidative phosphorylation. (AU) | |
| FAPESP's process: | 15/18269-1 - Using comparative genomics to understand convergent evolution of mammals: tracking the molecular footprints of the marine and riverine environment colonisation |
| Grantee: | Mariana Freitas Nery |
| Support Opportunities: | Research Grants - Young Investigators Grants |
| FAPESP's process: | 17/25058-2 - Adaptive convergent evolution of hematophagy-related genes in Insecta |
| Grantee: | Lucas Araujo Freitas |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 18/01236-1 - Evolution of new environments colonization in mammals: investigating the molecular footprints of fluvial environment colonization and the osmoregulation system |
| Grantee: | Elisa Karen da Silva Ramos |
| Support Opportunities: | Scholarships in Brazil - Doctorate |